Label-free Identification of Nonelectrogenic Cancer Cells using Adhesion Noise
Time-continuous detection of cells on substrates without the need of optical microscopic imaging is of broad interest in biotechnological applications. We present a method how to detect cancer cells using voltage noise caused by cell adhesion which is recorded by high-density CMOS-based microelectro...
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| Vydané v: | 2023 IEEE BioSensors Conference (BioSensors) s. 1 - 4 |
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| Hlavní autori: | , , , |
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| Jazyk: | English |
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30.07.2023
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| Abstract | Time-continuous detection of cells on substrates without the need of optical microscopic imaging is of broad interest in biotechnological applications. We present a method how to detect cancer cells using voltage noise caused by cell adhesion which is recorded by high-density CMOS-based microelectrode arrays. We analyze our data in terms of spectral power density for two different types of arrays, each of them being optimized in a different working regime. |
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| AbstractList | Time-continuous detection of cells on substrates without the need of optical microscopic imaging is of broad interest in biotechnological applications. We present a method how to detect cancer cells using voltage noise caused by cell adhesion which is recorded by high-density CMOS-based microelectrode arrays. We analyze our data in terms of spectral power density for two different types of arrays, each of them being optimized in a different working regime. |
| Author | Ell, Maximilian Zeck, Gunther Thewes, Roland Zeitler, Ralf |
| Author_xml | – sequence: 1 givenname: Maximilian surname: Ell fullname: Ell, Maximilian email: maximilian.ell@tuwien.ac.at organization: Institute of Biomedical Electronics,TU Wien, Faculty of Electrical Engineering and Information Technology,Vienna,Austria – sequence: 2 givenname: Ralf surname: Zeitler fullname: Zeitler, Ralf organization: zerodev,Stuttgart,Germany – sequence: 3 givenname: Roland surname: Thewes fullname: Thewes, Roland organization: Chair of Sensor and Actuator Systems,TU Berlin, Faculty of Electrical Engineering and Computer Science,Berlin,Germany – sequence: 4 givenname: Gunther surname: Zeck fullname: Zeck, Gunther organization: Institute of Biomedical Electronics,TU Wien, Faculty of Electrical Engineering and Information Technology,Vienna,Austria |
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| Snippet | Time-continuous detection of cells on substrates without the need of optical microscopic imaging is of broad interest in biotechnological applications. We... |
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| SubjectTerms | Adhesives Arrays Biosensors cell adhesion noise CMOS-based microelectrode array HT-29 cell Microelectrodes Optical recording Power system measurements Voltage |
| Title | Label-free Identification of Nonelectrogenic Cancer Cells using Adhesion Noise |
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