Electrical Recording of Effects of Chemotherapeutic Treatment on Cancer Spheroids

Monitoring cells on substrates time-continuously without relying on optical microscopy imaging is of broad interest in biotechnological applications. We propose an approach to electrically investigate cytotoxic effects of a chemotherapeutic treatment on cancer cells using cell adhesion noise spectro...

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Bibliographic Details
Published in:Proceedings of IEEE Sensors ... pp. 1 - 4
Main Authors: Ell, Maximilian, Bui, Mai Thu, Prado-Lopez, Sonia, Zeck, Gunther
Format: Conference Proceeding
Language:English
Published: IEEE 29.10.2023
Subjects:
Adhesives
anti-cancer therapeutics
cell adhesion noise spectroscopy
CMOS-based microelectrode array
colorectal cancer cells
Microelectrodes
Optical noise
Optical recording
Optical sensors
Power system measurements
Spectroscopy
spheroids
ISSN:2168-9229
Online Access:Get full text
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Summary:Monitoring cells on substrates time-continuously without relying on optical microscopy imaging is of broad interest in biotechnological applications. We propose an approach to electrically investigate cytotoxic effects of a chemotherapeutic treatment on cancer cells using cell adhesion noise spectroscopy. Recordings are taken with high-density microelectrode arrays, data are analyzed in terms of spectral power density.
ISSN:2168-9229
DOI:10.1109/SENSORS56945.2023.10325119