Electrical Recording of Effects of Chemotherapeutic Treatment on Cancer Spheroids
Monitoring cells on substrates time-continuously without relying on optical microscopy imaging is of broad interest in biotechnological applications. We propose an approach to electrically investigate cytotoxic effects of a chemotherapeutic treatment on cancer cells using cell adhesion noise spectro...
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| Published in: | Proceedings of IEEE Sensors ... pp. 1 - 4 |
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| Main Authors: | , , , |
| Format: | Conference Proceeding |
| Language: | English |
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IEEE
29.10.2023
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| ISSN: | 2168-9229 |
| Online Access: | Get full text |
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| Abstract | Monitoring cells on substrates time-continuously without relying on optical microscopy imaging is of broad interest in biotechnological applications. We propose an approach to electrically investigate cytotoxic effects of a chemotherapeutic treatment on cancer cells using cell adhesion noise spectroscopy. Recordings are taken with high-density microelectrode arrays, data are analyzed in terms of spectral power density. |
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| AbstractList | Monitoring cells on substrates time-continuously without relying on optical microscopy imaging is of broad interest in biotechnological applications. We propose an approach to electrically investigate cytotoxic effects of a chemotherapeutic treatment on cancer cells using cell adhesion noise spectroscopy. Recordings are taken with high-density microelectrode arrays, data are analyzed in terms of spectral power density. |
| Author | Ell, Maximilian Zeck, Gunther Bui, Mai Thu Prado-Lopez, Sonia |
| Author_xml | – sequence: 1 givenname: Maximilian surname: Ell fullname: Ell, Maximilian organization: Institute of Biomedical Electronics,TU Wien,Vienna,Austria – sequence: 2 givenname: Mai Thu surname: Bui fullname: Bui, Mai Thu organization: Institute of Biomedical Electronics,TU Wien,Vienna,Austria – sequence: 3 givenname: Sonia surname: Prado-Lopez fullname: Prado-Lopez, Sonia organization: Institute of Solid State Electronics,TU Wien,Vienna,Austria – sequence: 4 givenname: Gunther surname: Zeck fullname: Zeck, Gunther email: maximilian.ell@tuwien.ac.at organization: Institute of Biomedical Electronics,TU Wien,Vienna,Austria |
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| Snippet | Monitoring cells on substrates time-continuously without relying on optical microscopy imaging is of broad interest in biotechnological applications. We... |
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| SubjectTerms | Adhesives anti-cancer therapeutics cell adhesion noise spectroscopy CMOS-based microelectrode array colorectal cancer cells Microelectrodes Optical noise Optical recording Optical sensors Power system measurements Spectroscopy spheroids |
| Title | Electrical Recording of Effects of Chemotherapeutic Treatment on Cancer Spheroids |
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