Recent Developments in the Biological Activities, Bioproduction, and Applications of IPseudomonas/I spp. Phenazines

Phenazines are a large group of heterocyclic nitrogen-containing compounds with demonstrated insecticidal, antimicrobial, antiparasitic, and anticancer activities. These natural compounds are synthesized by several microorganisms originating from diverse habitats, including marine and terrestrial so...

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Vydáno v:Molecules (Basel, Switzerland) Ročník 28; číslo 3
Hlavní autoři: Serafim, Bruno, Bernardino, Ana R, Freitas, Filomena, Torres, Cristiana A. V
Médium: Journal Article
Jazyk:angličtina
Vydáno: MDPI AG 01.02.2023
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ISSN:1420-3049, 1420-3049
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Abstract Phenazines are a large group of heterocyclic nitrogen-containing compounds with demonstrated insecticidal, antimicrobial, antiparasitic, and anticancer activities. These natural compounds are synthesized by several microorganisms originating from diverse habitats, including marine and terrestrial sources. The most well-studied producers belong to the Pseudomonas genus, which has been extensively investigated over the years for its ability to synthesize phenazines. This review is focused on the research performed on pseudomonads’ phenazines in recent years. Their biosynthetic pathways, mechanism of regulation, production processes, bioactivities, and applications are revised in this manuscript.
AbstractList Phenazines are a large group of heterocyclic nitrogen-containing compounds with demonstrated insecticidal, antimicrobial, antiparasitic, and anticancer activities. These natural compounds are synthesized by several microorganisms originating from diverse habitats, including marine and terrestrial sources. The most well-studied producers belong to the Pseudomonas genus, which has been extensively investigated over the years for its ability to synthesize phenazines. This review is focused on the research performed on pseudomonads’ phenazines in recent years. Their biosynthetic pathways, mechanism of regulation, production processes, bioactivities, and applications are revised in this manuscript.
Audience Academic
Author Freitas, Filomena
Bernardino, Ana R
Torres, Cristiana A. V
Serafim, Bruno
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Heterocyclic compounds
Microbiological synthesis
Physiological aspects
Production processes
Pseudomonas
Title Recent Developments in the Biological Activities, Bioproduction, and Applications of IPseudomonas/I spp. Phenazines
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