Recent Developments in the Biological Activities, Bioproduction, and Applications of IPseudomonas/I spp. Phenazines
Phenazines are a large group of heterocyclic nitrogen-containing compounds with demonstrated insecticidal, antimicrobial, antiparasitic, and anticancer activities. These natural compounds are synthesized by several microorganisms originating from diverse habitats, including marine and terrestrial so...
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| Vydáno v: | Molecules (Basel, Switzerland) Ročník 28; číslo 3 |
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| Jazyk: | angličtina |
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MDPI AG
01.02.2023
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| ISSN: | 1420-3049, 1420-3049 |
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| Abstract | Phenazines are a large group of heterocyclic nitrogen-containing compounds with demonstrated insecticidal, antimicrobial, antiparasitic, and anticancer activities. These natural compounds are synthesized by several microorganisms originating from diverse habitats, including marine and terrestrial sources. The most well-studied producers belong to the Pseudomonas genus, which has been extensively investigated over the years for its ability to synthesize phenazines. This review is focused on the research performed on pseudomonads’ phenazines in recent years. Their biosynthetic pathways, mechanism of regulation, production processes, bioactivities, and applications are revised in this manuscript. |
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| AbstractList | Phenazines are a large group of heterocyclic nitrogen-containing compounds with demonstrated insecticidal, antimicrobial, antiparasitic, and anticancer activities. These natural compounds are synthesized by several microorganisms originating from diverse habitats, including marine and terrestrial sources. The most well-studied producers belong to the Pseudomonas genus, which has been extensively investigated over the years for its ability to synthesize phenazines. This review is focused on the research performed on pseudomonads’ phenazines in recent years. Their biosynthetic pathways, mechanism of regulation, production processes, bioactivities, and applications are revised in this manuscript. |
| Audience | Academic |
| Author | Freitas, Filomena Bernardino, Ana R Torres, Cristiana A. V Serafim, Bruno |
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| Copyright | COPYRIGHT 2023 MDPI AG |
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| DOI | 10.3390/molecules28031368 |
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| SubjectTerms | Biological products Chemical research Health aspects Heterocyclic compounds Microbiological synthesis Physiological aspects Production processes Pseudomonas |
| Title | Recent Developments in the Biological Activities, Bioproduction, and Applications of IPseudomonas/I spp. Phenazines |
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