Recent Developments in the Biological Activities, Bioproduction, and Applications of IPseudomonas/I spp. Phenazines

Phenazines are a large group of heterocyclic nitrogen-containing compounds with demonstrated insecticidal, antimicrobial, antiparasitic, and anticancer activities. These natural compounds are synthesized by several microorganisms originating from diverse habitats, including marine and terrestrial so...

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Veröffentlicht in:Molecules (Basel, Switzerland) Jg. 28; H. 3
Hauptverfasser: Serafim, Bruno, Bernardino, Ana R, Freitas, Filomena, Torres, Cristiana A. V
Format: Journal Article
Sprache:Englisch
Veröffentlicht: MDPI AG 01.02.2023
Schlagworte:
Biological products
Chemical research
Health aspects
Heterocyclic compounds
Microbiological synthesis
Physiological aspects
Production processes
Pseudomonas
Portugal
ISSN:1420-3049, 1420-3049
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Zusammenfassung:Phenazines are a large group of heterocyclic nitrogen-containing compounds with demonstrated insecticidal, antimicrobial, antiparasitic, and anticancer activities. These natural compounds are synthesized by several microorganisms originating from diverse habitats, including marine and terrestrial sources. The most well-studied producers belong to the Pseudomonas genus, which has been extensively investigated over the years for its ability to synthesize phenazines. This review is focused on the research performed on pseudomonads’ phenazines in recent years. Their biosynthetic pathways, mechanism of regulation, production processes, bioactivities, and applications are revised in this manuscript.
ISSN:1420-3049
1420-3049
DOI:10.3390/molecules28031368