Dating the origins of the maize-adapted strain of maize streak virus, MSV-A

Maize streak virus (MSV), which causes maize streak disease (MSD), is one of the most serious biotic threats to African food security. Here, we use whole MSV genomes sampled over 30 years to estimate the dates of key evolutionary events in the 500 year association of MSV and maize. The substitution...

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Veröffentlicht in:Journal of general virology Jg. 90; H. Pt 12; S. 3066
Hauptverfasser: Harkins, Gordon W, Martin, Darren P, Duffy, Siobain, Monjane, Aderito L, Shepherd, Dionne N, Windram, Oliver P, Owor, Betty E, Donaldson, Lara, van Antwerpen, Tania, Sayed, Rizwan A, Flett, Bradley, Ramusi, Moses, Rybicki, Edward P, Peterschmitt, Michel, Varsani, Arvind
Format: Journal Article
Sprache:Englisch
Veröffentlicht: England 01.12.2009
Schlagworte:
Bayes Theorem
Evolution, Molecular
Genome, Viral
Maize streak virus - classification
Maize streak virus - genetics
Maize streak virus - pathogenicity
Molecular Sequence Data
Plant Diseases - virology
Poaceae - virology
Recombination, Genetic
Sequence Analysis, DNA
Virulence
Zea mays - virology
ISSN:1465-2099, 1465-2099
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Zusammenfassung:Maize streak virus (MSV), which causes maize streak disease (MSD), is one of the most serious biotic threats to African food security. Here, we use whole MSV genomes sampled over 30 years to estimate the dates of key evolutionary events in the 500 year association of MSV and maize. The substitution rates implied by our analyses agree closely with those estimated previously in controlled MSV evolution experiments, and we use them to infer the date when the maize-adapted strain, MSV-A, was generated by recombination between two grass-adapted MSV strains. Our results indicate that this recombination event occurred in the mid-1800 s, approximately 20 years before the first credible reports of MSD in South Africa and centuries after the introduction of maize to the continent in the early 1500 s. This suggests a causal link between MSV recombination and the emergence of MSV-A as a serious pathogen of maize.
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ISSN:1465-2099
1465-2099
DOI:10.1099/vir.0.015537-0