Promoter Methylation Regulates Estrogen Receptor 2 in Human Endometrium and Endometriosis

Steroid receptors in the stromal cells of endometrium and its disease counterpart tissue endometriosis play critical physiologic roles. We found that mRNA and protein levels of estrogen receptor 2 (ESR2) were strikingly higher, whereas levels of estrogen receptor 1 (ESR1), total progesterone recepto...

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Bibliographic Details
Published in:	Biology of reproduction Vol. 77; no. 4; pp. 681 - 687
Main Authors:	Xue, Qing, Lin, Zhihong, Cheng, You-Hong, Huang, Chiang-Ching, Marsh, Erica, Yin, Ping, Milad, Magdy P, Confino, Edmond, Reierstad, Scott, Innes, Joy, Bulun, Serdar E
Format:	Journal Article
Language:	English
Published:	Madison, WI Society for the Study of Reproduction, Inc 01.10.2007 Society for the Study of Reproduction
Subjects:	Adult Azacitidine - analogs & derivatives Azacitidine - pharmacology Biological and medical sciences Cells, Cultured CpG Islands DNA Methylation Endometriosis - genetics Endometrium - drug effects Endometrium - metabolism Estrogen Receptor alpha - genetics Estrogen Receptor beta - genetics Female Female genital diseases Gene Expression Regulation - genetics Gynecology. Andrology. Obstetrics Humans Medical sciences Non tumoral diseases Promoter Regions, Genetic - drug effects Receptors, Progesterone - genetics RNA, Messenger - analysis RNA, Messenger - metabolism Stromal Cells - drug effects Stromal Cells - metabolism Human Estrogen receptor estradiol receptor 17β-Estradiol Endometriosis CpG island ESR2 Female genital diseases Promoter Ovary Uterus DNA Uterine diseases DNA methylation Methylation Endometrium Biological receptor
ISSN:	0006-3363, 1529-7268
Online Access:	Get full text
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