An in vitro test to demonstrate the inhibitory effect of homologous immune serum on the infectivity of Cowdria ruminantium

Homologous immune sheep serum inhibits the infectivity of mice for the Kümm stock of Cowdria ruminantium in an in vitro test. The presence of complement and an optimal ratio between the reagents are of cardinal importance. With the exception of the Ball 3 stock, there is no cross-inhibition between...

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Vydáno v:Onderstepoort journal of veterinary research Ročník 60; číslo 1; s. 69
Hlavní autor: Du Plessis, J L
Médium: Journal Article
Jazyk:angličtina
Vydáno: South Africa 01.03.1993
Témata:
Animals
Antibodies, Bacterial - immunology
Cross Reactions
Ehrlichia ruminantium - immunology
Female
Heartwater Disease - diagnosis
Heartwater Disease - immunology
Immune Sera
Mice
Rabbits
ISSN:0030-2465
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Shrnutí:Homologous immune sheep serum inhibits the infectivity of mice for the Kümm stock of Cowdria ruminantium in an in vitro test. The presence of complement and an optimal ratio between the reagents are of cardinal importance. With the exception of the Ball 3 stock, there is no cross-inhibition between the immune sera of sheep infected with several other heterologous stocks and the Kümm stock. The role played by the humoral component of the immune response in naturally acquired heartwater is unknown, but probably small compared to the cellular component.
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ISSN:0030-2465