Clonal hematopoiesis and nonhematologic disorders

Clonal expansions of mutated hematopoietic cells, termed clonal hematopoiesis, are common in aging humans. One expected consequence of mutation-associated clonal hematopoiesis is an increased risk of hematologic cancers, which has now been shown in several studies. However, the hematopoietic stem ce...

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Veröffentlicht in:	Blood Jg. 136; H. 14; S. 1606
1. Verfasser:	Jaiswal, Siddhartha
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.10.2020
Schlagworte:	Animals Biomarkers Cardiovascular Diseases - etiology Cardiovascular Diseases - metabolism Clonal Evolution - genetics Clonal Hematopoiesis - genetics Clonal Hematopoiesis - immunology Disease Susceptibility - immunology Genetic Association Studies Genetic Predisposition to Disease Hematopoiesis - genetics Hematopoiesis - immunology Humans Mutation Organ Specificity Phenotype Terminology as Topic
ISSN:	1528-0020, 1528-0020
Online-Zugang:	Weitere Angaben
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