Clonal hematopoiesis and nonhematologic disorders

Clonal expansions of mutated hematopoietic cells, termed clonal hematopoiesis, are common in aging humans. One expected consequence of mutation-associated clonal hematopoiesis is an increased risk of hematologic cancers, which has now been shown in several studies. However, the hematopoietic stem ce...

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Vydané v:	Blood Ročník 136; číslo 14; s. 1606
Hlavný autor:	Jaiswal, Siddhartha
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 01.10.2020
Predmet:	Animals Biomarkers Cardiovascular Diseases - etiology Cardiovascular Diseases - metabolism Clonal Evolution - genetics Clonal Hematopoiesis - genetics Clonal Hematopoiesis - immunology Disease Susceptibility - immunology Genetic Association Studies Genetic Predisposition to Disease Hematopoiesis - genetics Hematopoiesis - immunology Humans Mutation Organ Specificity Phenotype Terminology as Topic
ISSN:	1528-0020, 1528-0020
On-line prístup:	Zistit podrobnosti o prístupe
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