Comparison of the efficacy of a dentifrice containing 1.5% arginine and 1450ppm fluoride to a dentifrice containing 1450ppm fluoride alone in the management of early coronal caries as assessed using Quantitative Light-induced Fluorescence

To compare the efficacy of a new dentifrice containing 1.5% arginine, an insoluble calcium compound, and 1450ppm fluoride to a matched, positive control dentifrice containing 1450ppm fluoride in arresting and reversing early coronal caries lesions in children using Quantitative Light-induced Fluores...

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Veröffentlicht in:Journal of dentistry Jg. 41; H. S2; S. S29 - S34
Hauptverfasser: Srisilapanan, P., Korwanich, N., Yin, W., Chuensuwonkul, C., Mateo, L.R., Zhang, Y.P., Cummins, D., Ellwood, R.P.
Format: Journal Article
Sprache:Englisch
Veröffentlicht: Oxford Elsevier Ltd 01.08.2013
Elsevier Limited
Schlagworte:
Arginine
Arrest
Caries
Coronal
Dental care
Dental caries
Dentifrice
Enamel
Fluorides
Lesions
Methods
Mineralization
Reversal
Caries
Arrest
Arginine
Enamel
Coronal
Dentifrice
Reversal
Lesions
ISSN:0300-5712, 1879-176X
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Zusammenfassung:To compare the efficacy of a new dentifrice containing 1.5% arginine, an insoluble calcium compound, and 1450ppm fluoride to a matched, positive control dentifrice containing 1450ppm fluoride in arresting and reversing early coronal caries lesions in children using Quantitative Light-induced Fluorescence (QLF). 331 children from Chiang Mai, Thailand, aged 7–14 years, with one or more visible early enamel caries lesions on the upper anterior teeth, completed the study. The new dentifrice contained 1.5% arginine, an insoluble calcium compound, and 1450ppm fluoride, as sodium monofluorophosphate; the matched positive control contained 1450ppm fluoride only. Subjects brushed twice daily at home and additionally once on school days under teacher's supervision. Digital images of the upper six anterior teeth were captured at the baseline, 3- and 6-month examinations using a custom apparatus for reproducible acquisition of Quantitative Light-induced Fluorescence data. At the 3-month examination, the ΔQ (representing lesion volume) for the test group decreased from a mean of 28.62 at baseline to 20.53mm2% and for the positive control group to 23.38mm2%. The difference between groups was not statistically significant (p=0.055). At the 6-month examination, the ΔQ decreased for the test group to 15.85mm2% and for the positive control group to 20.35mm2%. The difference between groups was statistically significant (p<0.001). A new dentifrice containing 1.5% arginine, an insoluble calcium compound, and 1450ppm fluoride, as sodium monofluorophosphate, provided statistically significant superior efficacy in arresting and reversing active coronal caries lesions in children than brushing with a matched positive control dentifrice containing fluoride alone.
Bibliographie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
ISSN:0300-5712
1879-176X
DOI:10.1016/j.jdent.2010.04.005