Identification of T cell dysfunction molecular subtypes and exploration of potential immunotherapy targets in BRAF V600E-mutant colorectal cancer

Background Immunotherapy is an effective treatment for BRAF V600E-mutant colorectal cancer, but currently, only a few benefit from it. Therefore, exploring new immunotherapy strategies is essential. Methods We obtained RNA sequencing data and clinical information of colorectal cancer patients from t...

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Bibliographic Details
Published in:	Discover. Oncology Vol. 16; no. 1; pp. 163 - 20
Main Authors:	Gu, Tiefeng, Qi, Haonan, Wang, Jiaqi, Sun, Liangwei, Su, Yongqi, Hu, Hanqing
Format:	Journal Article
Language:	English
Published:	New York Springer US 12.02.2025 Springer Nature B.V Springer
Subjects:	Algorithms Analysis BRAF V600E Cancer Research Colorectal cancer Datasets Gene expression IDO1 Immunotherapy Internal Medicine Lymphocytes Machine learning Medical prognosis Medicine Medicine & Public Health Metastasis Molecular Medicine Molecular subtypes Mutation Oncology Radiotherapy Software Surgical Oncology BRAF V600E Molecular subtypes Immunotherapy Colorectal cancer Machine learning IDO1
ISSN:	2730-6011, 2730-6011
Online Access:	Get full text
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