Histological Transformation and Progression in Follicular Lymphoma: A Clonal Evolution Study

Follicular lymphoma (FL) is an indolent, yet incurable B cell malignancy. A subset of patients experience an increased mortality rate driven by two distinct clinical end points: histological transformation and early progression after immunochemotherapy. The nature of tumor clonal dynamics leading to...

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Bibliographic Details
Published in:	PLoS medicine Vol. 13; no. 12; p. e1002197
Main Authors:	Kridel, Robert, Chan, Fong Chun, Mottok, Anja, Boyle, Merrill, Farinha, Pedro, Tan, King, Meissner, Barbara, Bashashati, Ali, McPherson, Andrew, Roth, Andrew, Shumansky, Karey, Yap, Damian, Ben-Neriah, Susana, Rosner, Jamie, Smith, Maia A., Nielsen, Cydney, Giné, Eva, Telenius, Adele, Ennishi, Daisuke, Mungall, Andrew, Moore, Richard, Morin, Ryan D., Johnson, Nathalie A., Sehn, Laurie H., Tousseyn, Thomas, Dogan, Ahmet, Connors, Joseph M., Scott, David W., Steidl, Christian, Marra, Marco A., Gascoyne, Randy D., Shah, Sohrab P.
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 13.12.2016 Public Library of Science (PLoS)
Subjects:	Academic libraries Bioinformatics Biology Biology and Life Sciences Cancer Care and treatment Clonal Evolution Clone Cells Cloning Colleges & universities Computer and Information Sciences Development and progression Disease Progression Gene expression Gene mutations Genetic aspects Genomes Health aspects Humans Laboratories Lymphoma Lymphoma, Follicular - genetics Lymphoma, Follicular - physiopathology Lymphomas Medicine Medicine and Health Sciences Mutation Oncology Pathology Research and Analysis Methods Vancouver British Columbia Canada Canada
ISSN:	1549-1676, 1549-1277, 1549-1676
Online Access:	Get full text
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