Shared Genetic Factors of Anxiety and Depression Symptoms in a Brazilian Family-Based Cohort, the Baependi Heart Study

To investigate the phenotypic and genetic overlap between anxiety and depression symptoms in an admixed population from extended family pedigrees. Participants (n = 1,375) were recruited from a cohort of 93 families (mean age±SD 42±16.3, 57% female) in the rural town of Baependi, Brazil. The Hospita...

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Vydáno v:	PloS one Ročník 10; číslo 12; s. e0144255
Hlavní autoři:	Taporoski, Tâmara P., Negrão, André B., Horimoto, Andréa R. V. R., Duarte, Nubia E., Alvim, Rafael O., de Oliveira, Camila M., Krieger, José E., Schantz, Malcolm von, Vallada, Homero, Pereira, Alexandre C.
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States Public Library of Science 09.12.2015 Public Library of Science (PLoS)
Témata:	Adult Age Anxiety Anxiety - epidemiology Anxiety - genetics Behavior disorders Bivariate analysis Brazil - epidemiology Cardiology Care and treatment Cohort Studies Covariance Depression - epidemiology Depression - genetics Diagnosis Estimates Family Relations Female Genetic diversity Genetic factors Genetic Predisposition to Disease Genetic variance Genetics Genome-wide association studies Genome-Wide Association Study Genomes Heart Heart diseases Heritability Hospitals Humans Laboratories Male Medical schools Mental depression Middle Aged Pedigree Phenotype Physiology Population Psychiatry Risk factors Sex Factors Social Environment Studies Variance analysis Brazil
ISSN:	1932-6203, 1932-6203
On-line přístup:	Získat plný text
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