Genetic architecture of gene expression traits across diverse populations

For many complex traits, gene regulation is likely to play a crucial mechanistic role. How the genetic architectures of complex traits vary between populations and subsequent effects on genetic prediction are not well understood, in part due to the historical paucity of GWAS in populations of non-Eu...

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Bibliographic Details
Published in:	PLoS genetics Vol. 14; no. 8; p. e1007586
Main Authors:	Mogil, Lauren S., Andaleon, Angela, Badalamenti, Alexa, Dickinson, Scott P., Guo, Xiuqing, Rotter, Jerome I., Johnson, W. Craig, Im, Hae Kyung, Liu, Yongmei, Wheeler, Heather E.
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 10.08.2018 Public Library of Science (PLoS)
Subjects:	Analysis Antigens, Neoplasm - genetics Antigens, Neoplasm - metabolism Arteriosclerosis Asthma Bioinformatics Biology Biology and Life Sciences Biomedical research Black or African American - genetics Cell Adhesion Molecules - genetics Cell Adhesion Molecules - metabolism Chromosome Mapping Consortia Ecology and Environmental Sciences Ethnicity - genetics Funding Gene expression Gene Expression Regulation Gene Frequency Gene mapping Gene regulation Generalized linear models Genetic regulation Genetics Genetics, Population Genome-wide association studies Genome-Wide Association Study Genomes Genomics Genotypes Genotyping Techniques Hispanic or Latino - genetics Humans Medicine Medicine and Health Sciences Methods Models, Genetic Monocytes Multifactorial Inheritance Pediatrics People and Places Phenotype Physical Sciences Population Population genetics Prediction models Principal components analysis Quantitative Trait Loci Research and Analysis Methods Software Statistical analysis Studies Transcriptome White People - genetics Los Angeles California Chicago Illinois California United States > US Illinois
ISSN:	1553-7404, 1553-7390, 1553-7404
Online Access:	Get full text
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