Number of People Blind or Visually Impaired by Glaucoma Worldwide and in World Regions 1990 – 2010: A Meta-Analysis

To assess the number of individuals visually impaired or blind due to glaucoma and to examine regional differences and temporal changes in this parameter for the period from 1990 to 2012. As part of the Global Burden of Diseases (GBD) Study 2010, we performed a systematic literature review for the p...

Full description

Saved in:
Bibliographic Details
Published in:PloS one Vol. 11; no. 10; p. e0162229
Main Authors: Bourne, Rupert R. A., Taylor, Hugh R., Flaxman, Seth R., Keeffe, Jill, Leasher, Janet, Naidoo, Kovin, Pesudovs, Konrad, White, Richard A., Wong, Tien Y., Resnikoff, Serge, Jonas, Jost B.
Format: Journal Article
Language:English
Published: United States Public Library of Science 20.10.2016
Public Library of Science (PLoS)
Subjects:
Acuity
Analysis
Biology and Life Sciences
Blind people
Blindness
Blindness - diagnosis
Blindness - epidemiology
Blindness - etiology
Cataracts
Databases, Factual
Diabetes
Diabetic retinopathy
Disease
Epidemiology
Female
Glaucoma
Glaucoma - complications
Glaucoma - diagnosis
Global Burden of Disease - statistics & numerical data
Humans
Impairment
Literature reviews
Male
Medical research
Medicine and Health Sciences
Meta-analysis
Ophthalmology
People with disabilities
Physical Sciences
Population
Population studies
Populations
Prevalence
Public health
Research and Analysis Methods
Social Sciences
Software development tools
Statistical analysis
Studies
Systematic review
Vision, Low - diagnosis
Vision, Low - epidemiology
Vision, Low - etiology
Visual acuity
Visual impairment
Sydney New South Wales Australia
Singapore
Australia
United States > US
Central Europe
ISSN:1932-6203, 1932-6203
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:To assess the number of individuals visually impaired or blind due to glaucoma and to examine regional differences and temporal changes in this parameter for the period from 1990 to 2012. As part of the Global Burden of Diseases (GBD) Study 2010, we performed a systematic literature review for the period from 1980 to 2012. We primarily identified 14,908 relevant manuscripts, out of which 243 high-quality, population-based studies remained after review by an expert panel that involved application of selection criteria that dwelt on population representativeness and clarity of visual acuity methods used. Sixty-six specified the proportion attributable to glaucoma. The software tool DisMod-MR (Disease Modeling-Metaregression) of the GBD was used to calculate fraction of vision impairment due to glaucoma. In 2010, 2.1 million (95% Uncertainty Interval (UI):1.9,2.6) people were blind, and 4.2 (95% UI:3.7,5.8) million were visually impaired due to glaucoma. Glaucoma caused worldwide 6.6% (95% UI:5.9,7.9) of all blindness in 2010 and 2.2% (95% UI:2.0,2.8) of all moderate and severe visual impairment (MSVI). These figures were lower in regions with younger populations (<5% in South Asia) than in high-income regions with relatively old populations (>10%). From 1990 to 2010, the number of blind or visually impaired due to glaucoma increased by 0.8 million (95%UI:0.7, 1.1) or 62% and by 2.3 million (95%UI:2.1,3.5) or 83%, respectively. Percentage of global blindness caused by glaucoma increased between 1990 and 2010 from 4.4% (4.0,5.1) to 6.6%. Age-standardized prevalence of glaucoma related blindness and MSVI did not differ markedly between world regions nor between women. By 2010, one out of 15 blind people was blind due to glaucoma, and one of 45 visually impaired people was visually impaired, highlighting the increasing global burden of glaucoma.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
content type line 14
ObjectType-Feature-3
ObjectType-Evidence Based Healthcare-1
ObjectType-Article-1
ObjectType-Feature-2
content type line 23
ObjectType-Undefined-3
A list of the Vision Loss Expert Group members can be found in the Acknowledgments section and by accessing this site: http://www.anglia.ac.uk/ruskin/en/home/microsites/veru/other_research_areas/global_burden_of_diseases.html
Competing Interests: The authors have declared that no competing interests exist.
Conceived and designed the experiments: RRAB SRF RAW.Analyzed the data: SRF RAW.Wrote the paper: RRAB HRT JK JL KN KP TYW SR JBJ.
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0162229