Metabolite profiles and the risk of developing diabetes

Amino acid profiles could aid in diabetes risk assessment, as a five-amino-acid signature had highly significant associations with the development of future diabetes in two large, independent cohorts. Emerging technologies allow the high-throughput profiling of metabolic status from a blood specimen...

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Veröffentlicht in:	Nature medicine Jg. 17; H. 4; S. 448 - 453
Hauptverfasser:	Wang, Thomas J, Larson, Martin G, Vasan, Ramachandran S, Cheng, Susan, Rhee, Eugene P, McCabe, Elizabeth, Lewis, Gregory D, Fox, Caroline S, Jacques, Paul F, Fernandez, Céline, O'Donnell, Christopher J, Carr, Stephen A, Mootha, Vamsi K, Florez, Jose C, Souza, Amanda, Melander, Olle, Clish, Clary B, Gerszten, Robert E
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	New York Nature Publishing Group US 01.04.2011 Nature Publishing Group
Schlagworte:	631/1647/320 692/499 692/699/2743/137/773 Aged Amines Amino acids Amino Acids, Aromatic - blood Amino Acids, Branched-Chain - blood Biomarkers - blood Biomedical and Life Sciences Biomedicine Blood Blood sugar Body mass index Cancer Research Cardiology and Cardiovascular Disease Case-Control Studies Causality Clinical Medicine Cohort Studies Diabetes Diabetes Mellitus - blood Diabetes Mellitus - etiology Female Health aspects Health risks Humans Infectious Diseases Kardiologi och kardiovaskulära sjukdomar Klinisk medicin Liquid chromatography Logistic Models Longitudinal Studies Male Mass spectrometry Medical and Health Sciences Medicin och hälsovetenskap Metabolic Diseases Metabolism Metabolites Metabolome Middle Aged Molecular Medicine Neurosciences Pathogenesis Physiological aspects Predictive Value of Tests Prospective Studies Risk assessment Risk Factors Tandem Mass Spectrometry Sweden
ISSN:	1078-8956, 1546-170X, 1546-170X
Online-Zugang:	Volltext
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