Cell-Specific Detection of miR-375 Downregulation for Predicting the Prognosis of Esophageal Squamous Cell Carcinoma by miRNA In Situ Hybridization

MicroRNAs (miRNAs) play important roles in the regulation of genes associated with cancer development and progression. By the more deeply characterization of miRNAs' effect in cancer development, it requires a useful tool to investigate expression and distribution of a miRNA in cancer cells and...

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Veröffentlicht in:	PloS one Jg. 8; H. 1; S. e53582
Hauptverfasser:	Li, Jiangchao, Li, Xiaodong, Li, Yan, Yang, Hong, Wang, Lijing, Qin, Yanru, Liu, Haibo, Fu, Li, Guan, Xin-Yuan
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Public Library of Science 03.01.2013 Public Library of Science (PLoS)
Schlagworte:	Acids Apoptosis Biology Biomarkers Biomarkers, Tumor - metabolism Cancer Carcinoma, Squamous Cell - genetics Cases (containers) Cell growth Cell Line, Tumor Down-Regulation Enzymes Esophageal cancer Esophageal Neoplasms - genetics Esophageal Squamous Cell Carcinoma Esophagus Fluorescence Gene expression Gene Expression Profiling Gene Expression Regulation, Neoplastic Gene regulation Genetic aspects Human subjects Humans Hybridization In situ hybridization In Situ Hybridization - methods Laboratories Lung cancer Medical prognosis Medicine Metastases Metastasis MicroRNA MicroRNAs MicroRNAs - metabolism Microscopy, Fluorescence miRNA Neoplasm Metastasis Oligonucleotide Array Sequence Analysis Oncology Phosphatase Polymerase Chain Reaction Prognosis Solid tumors Squamous cell carcinoma Thoracic surgery Tissue Array Analysis - methods Tissues Treatment Outcome Tumor cell lines Tumors Hong Kong China China
ISSN:	1932-6203, 1932-6203
Online-Zugang:	Volltext
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