Generation of Induced Pluripotent Stem Cells from Human Nasal Epithelial Cells Using a Sendai Virus Vector

The generation of induced pluripotent stem cells (iPSCs) by introducing reprogramming factors into somatic cells is a promising method for stem cell therapy in regenerative medicine. Therefore, it is desirable to develop a minimally invasive simple method to create iPSCs. In this study, we generated...

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Bibliographic Details
Published in:	PloS one Vol. 7; no. 8; p. e42855
Main Authors:	Ono, Mizuho, Hamada, Yuko, Horiuchi, Yasue, Matsuo-Takasaki, Mami, Imoto, Yoshimasa, Satomi, Kaishi, Arinami, Tadao, Hasegawa, Mamoru, Fujioka, Tsuyoshi, Nakamura, Yukio, Noguchi, Emiko
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 13.08.2012 Public Library of Science (PLoS)
Subjects:	Anesthesia B cells Biology Biopsy Blood Cellular Reprogramming DNA methylation Efficiency Embryo cells Embryonic stem cells Epigenetic inheritance Epigenetics Epithelial cells Female Fibroblasts Gene expression Genes Genetic vectors Genetic Vectors - genetics Genomes Genomics Genotypes Health aspects Humans Induced Pluripotent Stem Cells - cytology Induced Pluripotent Stem Cells - metabolism Infections Lymphocytes Medical research Medicine Molecular modelling Morphology Nasal Mucosa - cytology Otolaryngology Pathogenesis Pluripotency Proteins Regenerative medicine Sendai virus - genetics Somatic cells Stem cell transplantation Stem cells Transduction, Genetic - methods Vectors Viruses Japan
ISSN:	1932-6203, 1932-6203
Online Access:	Get full text
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