Reduced Susceptibility of Plasmodium falciparum to Artesunate in Southern Myanmar

Plasmodium falciparum resistance to artemisinins, the first line treatment for malaria worldwide, has been reported in western Cambodia. Resistance is characterized by significantly delayed clearance of parasites following artemisinin treatment. Artemisinin resistance has not previously been reporte...

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Vydané v:	PloS one Ročník 8; číslo 3; s. e57689
Hlavní autori:	Kyaw, Myat P., Nyunt, Myat H., Chit, Khin, Aye, Moe M., Aye, Kyin H., Lindegardh, Niklas, Tarning, Joel, Imwong, Mallika, Jacob, Christopher G., Rasmussen, Charlotte, Perin, Jamie, Ringwald, Pascal, Nyunt, Myaing M.
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States Public Library of Science 08.03.2013 Public Library of Science (PLoS)
Predmet:	Adult Adults Antimalarials - administration & dosage Antimalarials - pharmacokinetics Artemisinin Artemisinins - administration & dosage Artemisinins - pharmacokinetics Artesunate Bioavailability Biology Cambodia - epidemiology Clearing Clinical medicine Clinical trials Containment Drug Resistance Erythrocytes Female Genomes Half-life Humans Infections Malaria Malaria, Falciparum - drug therapy Malaria, Falciparum - epidemiology Malaria, Falciparum - transmission Male Medical research Medicine Myanmar - epidemiology Parasitemia Parasites Pharmacokinetics Pharmacology Plasmodium falciparum Plasmodium falciparum - pathogenicity Plasmodium vivax Public health Smear Vector-borne diseases Cambodia Myanmar Myanmar (Burma) United States > US Thailand Maryland Baltimore Maryland Bangkok Thailand
ISSN:	1932-6203, 1932-6203
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