Infusion of gliotoxins or a gap junction blocker in the prelimbic cortex increases alcohol preference in Wistar rats

Postmortem research has revealed that there is a lower density of glial cells in regions of the prefrontal cortex (PFC) of uncomplicated alcoholics when compared with control subjects. Impairment of astrocyte function in the PFC may contribute to malfunction in circuits involved in emotion- and rewa...

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Bibliographic Details
Published in:	Journal of psychopharmacology (Oxford) Vol. 23; no. 5; p. 550
Main Authors:	Miguel-Hidalgo, J, Shoyama, Y, Wanzo, V
Format:	Journal Article
Language:	English
Published:	United States 01.07.2009
Subjects:	2-Aminoadipic Acid - pharmacology Alcohol Drinking - psychology Animals Astrocytes - drug effects Astrocytes - metabolism Citrates - pharmacology Gap Junctions - drug effects Gap Junctions - metabolism Gliotoxin - pharmacology Glycyrrhetinic Acid - analogs & derivatives Glycyrrhetinic Acid - pharmacology Male Neuroglia - drug effects Neuroglia - metabolism Prefrontal Cortex - drug effects Prefrontal Cortex - metabolism Rats Rats, Wistar
ISSN:	0269-8811
Online Access:	Get more information
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