Infusion of gliotoxins or a gap junction blocker in the prelimbic cortex increases alcohol preference in Wistar rats

Postmortem research has revealed that there is a lower density of glial cells in regions of the prefrontal cortex (PFC) of uncomplicated alcoholics when compared with control subjects. Impairment of astrocyte function in the PFC may contribute to malfunction in circuits involved in emotion- and rewa...

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Veröffentlicht in:	Journal of psychopharmacology (Oxford) Jg. 23; H. 5; S. 550
Hauptverfasser:	Miguel-Hidalgo, J, Shoyama, Y, Wanzo, V
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.07.2009
Schlagworte:	2-Aminoadipic Acid - pharmacology Alcohol Drinking - psychology Animals Astrocytes - drug effects Astrocytes - metabolism Citrates - pharmacology Gap Junctions - drug effects Gap Junctions - metabolism Gliotoxin - pharmacology Glycyrrhetinic Acid - analogs & derivatives Glycyrrhetinic Acid - pharmacology Male Neuroglia - drug effects Neuroglia - metabolism Prefrontal Cortex - drug effects Prefrontal Cortex - metabolism Rats Rats, Wistar
ISSN:	0269-8811
Online-Zugang:	Weitere Angaben
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