Genome of Acanthamoeba castellanii highlights extensive lateral gene transfer and early evolution of tyrosine kinase signaling

Background The Amoebozoa constitute one of the primary divisions of eukaryotes, encompassing taxa of both biomedical and evolutionary importance, yet its genomic diversity remains largely unsampled. Here we present an analysis of a whole genome assembly of Acanthamoeba castellanii ( Ac ) the first r...

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Bibliographic Details
Published in:	Genome biology Vol. 14; no. 2; p. R11
Main Authors:	Clarke, Michael, Lohan, Amanda J, Liu, Bernard, Lagkouvardos, Ilias, Roy, Scott, Zafar, Nikhat, Bertelli, Claire, Schilde, Christina, Kianianmomeni, Arash, Bürglin, Thomas R, Frech, Christian, Turcotte, Bernard, Kopec, Klaus O, Synnott, John M, Choo, Caleb, Paponov, Ivan, Finkler, Aliza, Heng Tan, Chris Soon, Hutchins, Andrew P, Weinmeier, Thomas, Rattei, Thomas, Chu, Jeffery SC, Gimenez, Gregory, Irimia, Manuel, Rigden, Daniel J, Fitzpatrick, David A, Lorenzo-Morales, Jacob, Bateman, Alex, Chiu, Cheng-Hsun, Tang, Petrus, Hegemann, Peter, Fromm, Hillel, Raoult, Didier, Greub, Gilbert, Miranda-Saavedra, Diego, Chen, Nansheng, Nash, Piers, Ginger, Michael L, Horn, Matthias, Schaap, Pauline, Caler, Lis, Loftus, Brendan J
Format:	Journal Article
Language:	English
Published:	London BioMed Central 01.02.2013
Subjects:	Acanthamoeba castellanii Acanthamoeba castellanii - genetics Amoebozoa Animal Genetics and Genomics Animalia bacteria Bioinformatics Biomedical and Life Sciences cell communication eukaryotic cells evolution Evolution, Molecular Evolutionary Biology Gene Transfer, Horizontal genes genetic variation genome assembly Genome, Protozoan genomics horizontal gene transfer Human Genetics immune system Introns Life Sciences Metazoa Microbial Genetics and Genomics Plant Genetics and Genomics Protein-Tyrosine Kinases - genetics Protein-Tyrosine Kinases - metabolism Protozoan Proteins - genetics Protozoan Proteins - metabolism receptors Signal Transduction transcription (genetics) viruses Mannose Binding Protein Acanthamoeba Castellanii Lateral Gene Transfer Tyrosine Kinase Signaling Intron Gain
ISSN:	1474-760X, 1465-6906, 1474-760X, 1465-6914
Online Access:	Get full text
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