The role of long non-coding RNAs in neurodevelopment, brain function and neurological disease

Long non-coding RNAs (lncRNAs) are transcripts with low protein-coding potential that represent a large proportion of the transcriptional output of the cell. Many lncRNAs exhibit features indicative of functionality including tissue-restricted expression, localization to distinct subcellular structu...

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Veröffentlicht in:	Philosophical transactions of the Royal Society of London. Series B. Biological sciences Jg. 369; H. 1652
Hauptverfasser:	Roberts, Thomas C, Morris, Kevin V, Wood, Matthew J A
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England 26.09.2014
Schlagworte:	Brain - metabolism Brain - physiology Epigenesis, Genetic - genetics Epigenesis, Genetic - physiology Humans Nervous System - growth & development Nervous System Diseases - genetics Nervous System Diseases - physiopathology RNA, Long Noncoding - genetics RNA, Long Noncoding - physiology neurodegeneration long non-coding RNA neurodevelopment brain epigenetics
ISSN:	1471-2970, 1471-2970
Online-Zugang:	Weitere Angaben
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