myofibroblast, a key cell in normal and pathological tissue repair

Myofibroblasts are characterized by their expression of α-smooth muscle actin, their enhanced contractility when compared to normal fibroblasts and their increased synthetic activity of extracellular matrix proteins. Myofibroblasts play an important role in normal tissue repair processes, particular...

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Bibliographic Details
Published in:	Cellular and molecular life sciences : CMLS Vol. 73; no. 6; pp. 1145 - 1157
Main Authors:	Darby, Ian A, Zakuan, Noraina, Billet, Fabrice, Desmoulière, Alexis
Format:	Journal Article
Language:	English
Published:	Cham Springer International Publishing 01.03.2016 Springer Nature B.V Springer Verlag
Subjects:	Actin Animals Apoptosis Biochemistry Biomedical and Life Sciences Biomedicine Cancer Cell Biology Cellular biology Cicatrix - metabolism Cicatrix - pathology Extracellular matrix fibroblasts Fibrosis Humans kidneys Life Sciences liver Muscle contraction muscles Myofibroblasts - cytology Myofibroblasts - metabolism Myofibroblasts - pathology Neoplasms - metabolism Neoplasms - pathology Pathology Protein expression Review Smooth muscle tissue repair Wound Healing Innervation Contractility Excessive scarring Fibrosis Extracellular matrix Cancer stroma α-Smooth muscle actin alpha-Smooth muscle actin
ISSN:	1420-682X, 1420-9071, 1420-9071
Online Access:	Get full text
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