Strength and fluoride release characteristics of a calcium fluoride based dental nanocomposite

Secondary caries and restoration fracture remain the two most common problems in restorative dentistry. Release of fluoride ions (F) could be a substantial benefit because F could enrich neighboring enamel or dentin to combat caries. The objective of this study was to incorporate novel CaF 2 nanopar...

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Vydáno v:Biomaterials Ročník 29; číslo 32; s. 4261 - 4267
Hlavní autoři: Xu, Hockin H.K., Moreau, Jennifer L., Sun, Limin, Chow, Laurence C.
Médium: Journal Article
Jazyk:angličtina
Vydáno: Netherlands Elsevier Ltd 01.11.2008
Témata:
Advanced Basic Science
CaF 2 nanoparticles
Calcium Fluoride - chemistry
Dental Materials - chemistry
Dental nanocomposite
Dentistry
Fluoride release
Fluorides - chemistry
Materials Testing
Microscopy, Electron, Transmission
Nanocomposites - chemistry
Nanocomposites - ultrastructure
Phosphorus - chemistry
Stress bearing
Tensile Strength
Tooth caries
X-Ray Diffraction
Tooth caries
CaF 2 nanoparticles
Dental nanocomposite
Stress bearing
Fluoride release
ISSN:0142-9612, 1878-5905
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Shrnutí:Secondary caries and restoration fracture remain the two most common problems in restorative dentistry. Release of fluoride ions (F) could be a substantial benefit because F could enrich neighboring enamel or dentin to combat caries. The objective of this study was to incorporate novel CaF 2 nanoparticles into dental resin to develop stress-bearing, F-releasing nanocomposite. CaF 2 nanoparticles, prepared in our laboratories for the first time, were combined with reinforcing whisker fillers in a resin. Flexural strength (mean ± sd; n = 6) was 110 ± 11 MPa for the composite containing 30% CaF 2 and 35% whiskers by mass. It matched the 108 ± 19 MPa of a stress-bearing, non-releasing commercial composite (Tukey's at 0.05). The composite containing 20% CaF 2 had a cumulative F release of 2.34 ± 0.26 mmol/L at 10 weeks. The initial F release rate was 2 μg/(h cm 2), and the sustained release rate after 10 weeks was 0.29 μg/(h cm 2). These values exceeded the reported releases of traditional and resin-modified glass ionomer materials. In summary, nanocomposites were developed with relatively high strength as well as sustained release of fluoride ions, a combination not available in current materials. These strong and F-releasing composites may yield restorations that can reduce the occurrence of both secondary caries and restoration fracture.
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ISSN:0142-9612
1878-5905
DOI:10.1016/j.biomaterials.2008.07.037