Muscle Regeneration with Intermuscular Adipose Tissue (IMAT) Accumulation Is Modulated by Mechanical Constraints

Sports trauma are able to induce muscle injury with fibrosis and accumulation of intermuscular adipose tissue (IMAT), which affect muscle function. This study was designed to investigate whether hypoactivity would influence IMAT accumulation in regenerating mouse skeletal muscle using the glycerol m...

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Veröffentlicht in:	PloS one Jg. 10; H. 12; S. e0144230
Hauptverfasser:	Pagano, Allan F., Demangel, Rémi, Brioche, Thomas, Jublanc, Elodie, Bertrand-Gaday, Christelle, Candau, Robin, Dechesne, Claude A., Dani, Christian, Bonnieu, Anne, Py, Guillaume, Chopard, Angèle
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Public Library of Science 02.12.2015 Public Library of Science (PLoS)
Schlagworte:	Accumulation Adipocytes Adipocytes - metabolism Adipocytes - physiology Adipogenesis Adipogenesis - physiology Adipose tissue Adipose Tissue - metabolism Adipose Tissue - physiology Analysis Animals Apoptosis Bioaccumulation Body fat Body weight CCAAT-Enhancer-Binding Proteins - metabolism Cell surface Experiments Fibrosis Gene expression Genes Glycerol Hindlimb Suspension - physiology Injection Laboratory animals Life Sciences Markers Mechanical unloading Mice Microgravity mRNA Muscle function Muscle, Skeletal - metabolism Muscle, Skeletal - physiology Muscles Muscular dystrophy Musculoskeletal system Physiology PPAR gamma - metabolism Recruitment Regeneration Regeneration - physiology RNA RNA, Messenger - metabolism Rodents Skeletal muscle Soleus muscle Stem cells Studies Surface markers Trauma Unloading muscle regénération musculaire
ISSN:	1932-6203, 1932-6203
Online-Zugang:	Volltext
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