Initiation of bacteriophage T4 DNA replication and replication fork dynamics: a review in the Virology Journal series on bacteriophage T4 and its relatives

Bacteriophage T4 initiates DNA replication from specialized structures that form in its genome. Immediately after infection, RNA-DNA hybrids (R-loops) occur on (at least some) replication origins, with the annealed RNA serving as a primer for leading-strand synthesis in one direction. As the infecti...

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Bibliographic Details
Published in:	Virology journal Vol. 7; no. 1; p. 358
Main Authors:	Kreuzer, Kenneth N, Brister, J Rodney
Format:	Journal Article
Language:	English
Published:	London BioMed Central 03.12.2010 BioMed Central Ltd Springer Nature B.V BMC
Subjects:	Bacteriophage T4 - enzymology Bacteriophage T4 - physiology Bacteriophage T4 and its relatives (A series of critical reviews) Bacteriophages Biomedical and Life Sciences Biomedicine Deoxyribonucleic acid DNA DNA repair DNA Replication DNA, Viral - metabolism Genetic aspects genome Genomes genomics Health aspects Mitochondrial DNA Models, Biological Plasmids Proteins Recombination, Genetic Replication fork Replication Origin Review RNA Studies two-dimensional gel electrophoresis Viral Proteins - metabolism Virology Virus Replication United States Phage Genome Replicative Helicase Replication Fork Fork Regression Strand Switching
ISSN:	1743-422X, 1743-422X
Online Access:	Get full text
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