Long Non-Coding RNA-ROR Mediates the Reprogramming in Cardiac Hypertrophy

Cardiac hypertrophy associated with various cardiovascular diseases results in heart failure and sudden death. A clear understanding of the mechanisms of hypertrophy will benefit the development of novel therapies. Long non-coding RNAs (lncRNAs) have been shown to play essential roles in many biolog...

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Bibliographic Details
Published in:	PloS one Vol. 11; no. 4; p. e0152767
Main Authors:	Jiang, Feng, Zhou, Xiangyu, Huang, Jing
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 15.04.2016 Public Library of Science (PLoS)
Subjects:	Animals Biological activity Biology and Life Sciences Cardiology Cardiomegaly - genetics Cardiomegaly - pathology Cardiomyocytes Cardiovascular diseases Coronary artery disease Coronary vessels Deoxyribonucleic acid DNA DNA damage Gene expression Gene Expression Regulation - drug effects Gene Knockdown Techniques Genetic aspects Heart diseases Heart failure Heart hypertrophy Hospitals Hypertrophy Kinases Laboratory animals Male Medicine and Health Sciences Mice Mice, Inbred C57BL MicroRNA MicroRNAs MicroRNAs - genetics Myocytes, Cardiac - drug effects Myocytes, Cardiac - pathology Non-coding RNA Pathogenesis Phenylephrine Phenylephrine - pharmacology Physiological aspects Plasmids Research and Analysis Methods Ribonucleic acid Risk factors RNA RNA, Long Noncoding - genetics RNA, Long Noncoding - metabolism Stem cells Ventilators China
ISSN:	1932-6203, 1932-6203
Online Access:	Get full text
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