Identification and Characterization of Ixodes scapularis Antigens That Elicit Tick Immunity Using Yeast Surface Display

Repeated exposure of rabbits and other animals to ticks results in acquired resistance or immunity to subsequent tick bites and is partially elicited by antibodies directed against tick antigens. In this study we demonstrate the utility of a yeast surface display approach to identify tick salivary a...

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Bibliographic Details
Published in:	PloS one Vol. 6; no. 1; p. e15926
Main Authors:	Schuijt, Tim J., Narasimhan, Sukanya, Daffre, Sirlei, DePonte, Kathleen, Hovius, Joppe W. R., Veer, Cornelis van't, van der Poll, Tom, Bakhtiari, Kamran, Meijers, Joost C. M., Boder, Eric T., van Dam, Alje P., Fikrig, Erol
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 05.01.2011 Public Library of Science (PLoS)
Subjects:	Acari Animal bites Animals Antibodies Antigens Antigens - blood Antigens - immunology Antigens - isolation & purification Antisera Arachnids Baking yeast Biology Bites Bites (Injuries) Borrelia Breast cancer Cell cycle Coagulants Drosophila Feeding Identification Immune serum Immunity Immunization Immunization - methods Immunoglobulins Insect bites Insects Internal medicine Ixodes - immunology Ixodes ricinus Ixodidae Libraries Medicine Neurogenesis Nymph Pathogens Peptide Library Proteins Rabbits Saccharomyces cerevisiae Salivary gland Salivary Glands - immunology Sexes Ticks Ticks - immunology Vectors (Biology) Yeast Yeasts Zoonoses United States > US Connecticut
ISSN:	1932-6203, 1932-6203
Online Access:	Get full text
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