Single plasmonic nanoparticles for biosensing

Along with remarkable progress of nanoplasmonics over the past 10 years, single plasmonic nanoparticle sensors have introduced a completely new dimension to the sensing scale, considering that nanoparticles are comparable in size to biomolecules such as nucleic acids or antibodies. Single particle s...

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Vydáno v:	Trends in biotechnology (Regular ed.) Ročník 29; číslo 7; s. 343 - 351
Hlavní autoři:	Sannomiya, Takumi, Vörös, Janos
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	Cambridge, MA Elsevier Ltd 01.07.2011 Cell Press Elsevier Limited
Témata:	adsorption antibodies Atoms & subatomic particles Biological and medical sciences Biomolecules Biosensing Techniques - methods Biosensors Biotechnology Detection diagnostic techniques drugs Fundamental and applied biological sciences. Psychology Internal Medicine Metal Nanoparticles Methods. Procedures. Technologies Nanocomposites Nanoparticles Nanostructure Nanotechnology - methods Nucleic acids Plasmonics Sensors Spectrum analysis Studies Surface Plasmon Resonance Various methods and equipments Nanoparticle Biosensor Review
ISSN:	0167-7799, 1879-3096, 1879-3096
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Abstract	Along with remarkable progress of nanoplasmonics over the past 10 years, single plasmonic nanoparticle sensors have introduced a completely new dimension to the sensing scale, considering that nanoparticles are comparable in size to biomolecules such as nucleic acids or antibodies. Single particle sensing methods have recently shown the possibility of detecting the adsorption of single biomolecules, and have already provided information about conformational changes of single molecules. For practical application, arrays of such compact sensor units are expected to realize massive multiplexing and high throughput in diagnostics and drug discovery in the near future. In this review, recent achievements and perspectives of this emerging biosensing technique are discussed.
AbstractList	Along with remarkable progress of nanoplasmonics over the past 10 years, single plasmonic nanoparticle sensors have introduced a completely new dimension to the sensing scale, considering that nanoparticles are comparable in size to biomolecules such as nucleic acids or antibodies. Single particle sensing methods have recently shown the possibility of detecting the adsorption of single biomolecules, and have already provided information about conformational changes of single molecules. For practical application, arrays of such compact sensor units are expected to realize massive multiplexing and high throughput in diagnostics and drug discovery in the near future. In this review, recent achievements and perspectives of this emerging biosensing technique are discussed. Along with remarkable progress of nanoplasmonics over the past 10 years, single plasmonic nanoparticle sensors have introduced a completely new dimension to the sensing scale, considering that nanoparticles are comparable in size to biomolecules such as nucleic acids or antibodies. Single particle sensing methods have recently shown the possibility of detecting the adsorption of single biomolecules, and have already provided information about conformational changes of single molecules. For practical application, arrays of such compact sensor units are expected to realize massive multiplexing and high throughput in diagnostics and drug discovery in the near future. In this review, recent achievements and perspectives of this emerging biosensing technique are discussed. Along with remarkable progress of nanoplasmonics over the past 10years, single plasmonic nanoparticle sensors have introduced a completely new dimension to the sensing scale, considering that nanoparticles are comparable in size to biomolecules such as nucleic acids or antibodies. Single particle sensing methods have recently shown the possibility of detecting the adsorption of single biomolecules, and have already provided information about conformational changes of single molecules. For practical application, arrays of such compact sensor units are expected to realize massive multiplexing and high throughput in diagnostics and drug discovery in the near future. In this review, recent achievements and perspectives of this emerging biosensing technique are discussed. Along with remarkable progress of nanoplasmonics over the past 10 years, single plasmonic nanoparticle sensors have introduced a completely new dimension to the sensing scale, considering that nanoparticles are comparable in size to biomolecules such as nucleic acids or antibodies. Single particle sensing methods have recently shown the possibility of detecting the adsorption of single biomolecules, and have already provided information about conformational changes of single molecules. For practical application, arrays of such compact sensor units are expected to realize massive multiplexing and high throughput in diagnostics and drug discovery in the near future. In this review, recent achievements and perspectives of this emerging biosensing technique are discussed.Along with remarkable progress of nanoplasmonics over the past 10 years, single plasmonic nanoparticle sensors have introduced a completely new dimension to the sensing scale, considering that nanoparticles are comparable in size to biomolecules such as nucleic acids or antibodies. Single particle sensing methods have recently shown the possibility of detecting the adsorption of single biomolecules, and have already provided information about conformational changes of single molecules. For practical application, arrays of such compact sensor units are expected to realize massive multiplexing and high throughput in diagnostics and drug discovery in the near future. In this review, recent achievements and perspectives of this emerging biosensing technique are discussed.
Author	Sannomiya, Takumi Vörös, Janos
Author_xml	– sequence: 1 givenname: Takumi surname: Sannomiya fullname: Sannomiya, Takumi email: sannomiya@biomed.ee.ethz.ch, 3.takumi@gmail.com – sequence: 2 givenname: Janos surname: Vörös fullname: Vörös, Janos
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Snippet	Along with remarkable progress of nanoplasmonics over the past 10 years, single plasmonic nanoparticle sensors have introduced a completely new dimension to... Along with remarkable progress of nanoplasmonics over the past 10 years, single plasmonic nanoparticle sensors have introduced a completely new dimension to... Along with remarkable progress of nanoplasmonics over the past 10years, single plasmonic nanoparticle sensors have introduced a completely new dimension to the...
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SubjectTerms	adsorption antibodies Atoms & subatomic particles Biological and medical sciences Biomolecules Biosensing Techniques - methods Biosensors Biotechnology Detection diagnostic techniques drugs Fundamental and applied biological sciences. Psychology Internal Medicine Metal Nanoparticles Methods. Procedures. Technologies Nanocomposites Nanoparticles Nanostructure Nanotechnology - methods Nucleic acids Plasmonics Sensors Spectrum analysis Studies Surface Plasmon Resonance Various methods and equipments
Title	Single plasmonic nanoparticles for biosensing
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