Single plasmonic nanoparticles for biosensing

Along with remarkable progress of nanoplasmonics over the past 10 years, single plasmonic nanoparticle sensors have introduced a completely new dimension to the sensing scale, considering that nanoparticles are comparable in size to biomolecules such as nucleic acids or antibodies. Single particle s...

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Bibliographic Details
Published in:Trends in biotechnology (Regular ed.) Vol. 29; no. 7; pp. 343 - 351
Main Authors: Sannomiya, Takumi, Vörös, Janos
Format: Journal Article
Language:English
Published: Cambridge, MA Elsevier Ltd 01.07.2011
Cell Press
Elsevier Limited
Subjects:
adsorption
antibodies
Atoms & subatomic particles
Biological and medical sciences
Biomolecules
Biosensing Techniques - methods
Biosensors
Biotechnology
Detection
diagnostic techniques
drugs
Fundamental and applied biological sciences. Psychology
Internal Medicine
Metal Nanoparticles
Methods. Procedures. Technologies
Nanocomposites
Nanoparticles
Nanostructure
Nanotechnology - methods
Nucleic acids
Plasmonics
Sensors
Spectrum analysis
Studies
Surface Plasmon Resonance
Various methods and equipments
Nanoparticle
Biosensor
Review
ISSN:0167-7799, 1879-3096, 1879-3096
Online Access:Get full text
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Summary:Along with remarkable progress of nanoplasmonics over the past 10 years, single plasmonic nanoparticle sensors have introduced a completely new dimension to the sensing scale, considering that nanoparticles are comparable in size to biomolecules such as nucleic acids or antibodies. Single particle sensing methods have recently shown the possibility of detecting the adsorption of single biomolecules, and have already provided information about conformational changes of single molecules. For practical application, arrays of such compact sensor units are expected to realize massive multiplexing and high throughput in diagnostics and drug discovery in the near future. In this review, recent achievements and perspectives of this emerging biosensing technique are discussed.
Bibliography:http://dx.doi.org/10.1016/j.tibtech.2011.03.003
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ISSN:0167-7799
1879-3096
1879-3096
DOI:10.1016/j.tibtech.2011.03.003