Discovery and validation of a personalized risk predictor for incident tuberculosis in low transmission settings

The risk of tuberculosis (TB) is variable among individuals with latent Mycobacterium tuberculosis infection (LTBI), but validated estimates of personalized risk are lacking. In pooled data from 18 systematically identified cohort studies from 20 countries, including 80,468 individuals tested for LT...

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Bibliographic Details
Published in:	NATURE MEDICINE Vol. 26; no. 12; pp. 1941 - 1949
Main Authors:	Gupta, Rishi K., Calderwood, Claire J., Yavlinsky, Alexei, Krutikov, Maria, Quartagno, Matteo, Aichelburg, Maximilian C., Altet, Neus, Diel, Roland, Dobler, Claudia C., Dominguez, Jose, Doyle, Joseph S., Erkens, Connie, Geis, Steffen, Haldar, Pranabashis, Hauri, Anja M., Hermansen, Thomas, Johnston, James C., Lange, Christoph, Lange, Berit, van Leth, Frank, Muñoz, Laura, Roder, Christine, Romanowski, Kamila, Roth, David, Sester, Martina, Sloot, Rosa, Sotgiu, Giovanni, Woltmann, Gerrit, Yoshiyama, Takashi, Zellweger, Jean-Pierre, Zenner, Dominik, Aldridge, Robert W., Copas, Andrew, Rangaka, Molebogeng X., Lipman, Marc, Noursadeghi, Mahdad, Abubakar, Ibrahim
Format:	Journal Article Publication
Language:	English
Published:	New York Nature Publishing Group US 01.12.2020 Nature Publishing Group
Subjects:	692/308 692/499 692/53 692/699 Adolescent Adult Biomedical and Life Sciences Biomedicine Cancer Research Child Confidence intervals Customization Decision analysis Decision making Female Humans Identification and classification Infectious Diseases Latent Tuberculosis - diagnosis Latent Tuberculosis - epidemiology Latent Tuberculosis - microbiology Lymphocytes Lymphocytes T Male Metabolic Diseases Molecular Medicine Mycobacterium tuberculosis - pathogenicity Neurosciences Prognosis Risk Risk Factors Risk factors (Health) Risk groups Statistical analysis Tuberculin Test Tuberculosis Tuberculosis - diagnosis Tuberculosis - epidemiology Tuberculosis - microbiology United Kingdom
ISSN:	1078-8956, 1546-170X, 1546-170X
Online Access:	Get full text
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