Fetal growth restriction promotes physical inactivity and obesity in female mice

Background: Environmental exposures during critical periods of prenatal and early postnatal life affect the development of mammalian body weight regulatory mechanisms, influencing lifelong risk of obesity. The specific biological processes that mediate the persistence of such effects, however, remai...

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Bibliographic Details
Published in:	International Journal of Obesity Vol. 39; no. 1; pp. 98 - 104
Main Authors:	Baker, M S, Li, G, Kohorst, J J, Waterland, R A
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 01.01.2015 Nature Publishing Group
Subjects:	631/136 692/699/2743/393 Adults Animals Animals, Newborn Biological activity Body composition Body weight Change detection Development and progression Diabetes mellitus Diabetic nephropathy DNA Methylation Eating Energy Energy expenditure Energy measurement Epidemiology Exercise Famine Female Females Fetal Growth Retardation - metabolism Fetal Growth Retardation - physiopathology Fetus Fetuses Food Food composition Food intake Genetic crosses Growth Growth retardation Health aspects Health Promotion and Disease Prevention Health risk assessment Hypothalamus - metabolism Hypothalamus - physiopathology Industrialized nations Internal Medicine Intrauterine exposure Kidney diseases Medical schools Medicine Medicine & Public Health Metabolic Diseases Metabolism Mice Mothers Motor Activity Nephropathy Nutrition research Obesity Obesity - metabolism Obesity - physiopathology Offspring original-article Pediatrics Physical activity Physiological effects Physiology Pregnancy Prenatal Exposure Delayed Effects - metabolism Prenatal Exposure Delayed Effects - physiopathology Prenatal influences Proteins Public Health Regression analysis Regulatory mechanisms (biology) Risk factors Sedentary behavior Suckling behavior Weaning Women United States United States > US developmental origins body weight regulation energy expenditure metabolic imprinting developmental programming physical activity
ISSN:	0307-0565, 1476-5497, 1476-5497
Online Access:	Get full text
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