Dendritic cell biology and its role in tumor immunotherapy

As crucial antigen presenting cells, dendritic cells (DCs) play a vital role in tumor immunotherapy. Taking into account the many recent advances in DC biology, we discuss how DCs (1) recognize pathogenic antigens with pattern recognition receptors through specific phagocytosis and through non-speci...

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Bibliographic Details
Published in:	Journal of hematology and oncology Vol. 13; no. 1; pp. 107 - 18
Main Authors:	Wang, Yingying, Xiang, Ying, Xin, Victoria W., Wang, Xian-Wang, Peng, Xiao-Chun, Liu, Xiao-Qin, Wang, Dong, Li, Na, Cheng, Jun-Ting, Lyv, Yan-Ning, Cui, Shu-Zhong, Ma, Zhaowu, Zhang, Qing, Xin, Hong-Wu
Format:	Journal Article
Language:	English
Published:	London BioMed Central 03.08.2020 BioMed Central Ltd Springer Nature B.V BMC
Subjects:	Animals Antigen (tumor-associated) Antigen presentation Antigen Presentation - immunology Antigen-presenting cells Antigens Antigens, Neoplasm - immunology Autophagy Autophagy - immunology Cancer Research Carbohydrates Caspase-11 CD4 antigen CD8 antigen Cell adhesion & migration Chemokines Clinical trials Clinical Trials as Topic Cytokines Dendritic cells Dendritic cells (DCs) Dendritic Cells - immunology Exosomes Exosomes - immunology Hematology Histocompatibility antigen HLA Histocompatibility Antigens Class I - immunology Humans Immune cells Immune response Immunoglobulin G Immunologic Memory Immunologic Surveillance Immunological memory Immunosurveillance Immunotherapy Lectins Lectins, C-Type - immunology Lymphocyte Activation Lymphocyte Subsets - immunology Lymphocytes Lymphocytes T Major histocompatibility complex Medical research Medicine Medicine & Public Health Medicine, Experimental Melanoma Memory cells MHC Mice Models, Immunological Neoantigens Neoplasms - immunology Neoplasms - therapy Oncology Pathogens Pattern recognition receptors Peptides Phagocytosis Physiology Protein Conformation Proteins Receptors, Antigen, T-Cell - chemistry Receptors, Antigen, T-Cell - immunology Receptors, Fc - immunology Receptors, Immunologic - immunology Review T cell receptors Tumor antigens Tumor immunotherapy Tumor Microenvironment Tumors Vaccines MHC Tumor immunotherapy Dendritic cells (DCs) Immune cells
ISSN:	1756-8722, 1756-8722
Online Access:	Get full text
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