Pan-cancer analysis reveals tumor-associated macrophage communication in the tumor microenvironment

Background Tumor-associated macrophages (TAMs) are abundant in the tumor microenvironment (TME). However, their contribution to the immunosuppressive status of the TME remains unclear. Methods We integrated single-cell sequencing and transcriptome data from different tumor types to uncover the molec...

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Bibliographic Details
Published in:	Experimental hematology & oncology Vol. 10; no. 1; pp. 31 - 19
Main Authors:	Wang, Linbang, He, Tao, Liu, Jingkun, Tai, Jiaojiao, Wang, Bing, Chen, Zhiyu, Quan, Zhengxue
Format:	Journal Article
Language:	English
Published:	London BioMed Central 10.05.2021 BioMed Central Ltd Springer Nature B.V BMC
Subjects:	Analysis Cancer Cancer Research Communication Cytokines Development and progression FLI1 Gene expression Genotype & phenotype Hematology Immunotherapy Intercellular communication Ligands Macrophages Medical prognosis Medicine Medicine & Public Health Melanoma Oncology Principal components analysis Tumor microenvironment Tumor-associated macrophages Tumors China Tumor microenvironment Tumor-associated macrophages Intercellular communication FLI1
ISSN:	2162-3619, 2162-3619
Online Access:	Get full text
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