Variability of risk factors and diabetes complications

Several studies suggest that, together with glucose variability, the variability of other risk factors, as blood pressure, plasma lipids, heart rate, body weight, and serum uric acid, might play a role in the development of diabetes complications. Moreover, the variability of each risk factor, when...

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Veröffentlicht in:Cardiovascular Diabetology Jg. 20; H. 1; S. 101 - 11
Hauptverfasser: Ceriello, Antonio, Prattichizzo, Francesco
Format: Journal Article
Sprache:Englisch
Veröffentlicht: London Springer Science and Business Media LLC 07.05.2021
BioMed Central
Springer Nature B.V
BMC
Schlagworte:
Angiology
Blood pressure
Blood pressure variability
Body weight
Body weight variability
Cardiology
Cardiovascular disease
Cholesterol
Diabetes
Diabetes Complications
Diabetes mellitus
Diseases of the circulatory (Cardiovascular) system
Glucose variability
Heart attacks
Heart failure
Heart rate
Humans
Hypertension
Insulin
Lipids
Lipids variability
Medicine
Medicine & Public Health
Mortality
Oxidative stress
Prognosis
RC666-701
Review
Risk Assessment
Risk Factors
Triglycerides
Uric acid
Uric acid variability
Glucose variability
Oxidative stress
Diabetes mellitus
Blood pressure variability
Body weight variability
Uric acid variability
Microvascular complications
Heart rate variability
Lipids variability
Cardiovascular complications
ISSN:1475-2840, 1475-2840
Online-Zugang:Volltext
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Zusammenfassung:Several studies suggest that, together with glucose variability, the variability of other risk factors, as blood pressure, plasma lipids, heart rate, body weight, and serum uric acid, might play a role in the development of diabetes complications. Moreover, the variability of each risk factor, when contemporarily present, may have additive effects. However, the question is whether variability is causal or a marker. Evidence shows that the quality of care and the attainment of the target impact on the variability of all risk factors. On the other hand, for some of them causality may be considered. Although specific studies are still lacking, it should be useful checking the variability of a risk factor, together with its magnitude out of the normal range, in clinical practice. This can lead to an improvement of the quality of care, which, in turn, could further hesitate in an improvement of risk factors variability.
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ISSN:1475-2840
1475-2840
DOI:10.1186/s12933-021-01289-4