Role of immune cells in the removal of deleterious senescent cells

Cellular senescence is an essentially irreversible arrest of cell proliferation coupled to a complex senescence-associated secretory phenotype (SASP). The senescence arrest prevents the development of cancer, and the SASP can promote tissue repair. Recent data suggest that the prolonged presence of...

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Bibliographic Details
Published in:	Immunity & ageing Vol. 17; no. 1; pp. 16 - 9
Main Authors:	Kale, Abhijit, Sharma, Amit, Stolzing, Alexandra, Desprez, Pierre-Yves, Campisi, Judith
Format:	Journal Article
Language:	English
Published:	London BioMed Central 03.06.2020 BioMed Central Ltd Springer Nature B.V BMC
Subjects:	Age Age-related pathology Aging Antibodies Arthritis Atherosclerosis BASIC BIOLOGICAL SCIENCES Biomedical and Life Sciences Biomedicine Cancer Care and treatment Cell cycle Cell proliferation Cell-based therapy Cellular senescence Chemokines Clinical Nutrition Cyclin-dependent kinases Cytokines Deoxyribonucleic acid Disease DNA Drugs Genotype & phenotype Geriatrics/Gerontology Health aspects Homeostasis Immune surveillance Immune system Immunology Inflammation Ionizing radiation Killer cells Kinases Macrophages Natural killer cells Neutrophils Nitric oxide Pathogens Phenotypes Prevention Public Health Review Senescence Tumor necrosis factor-TNF Cellular senescence Cell-based therapy Immune surveillance Inflammation Natural killer cells Macrophages Age-related pathology
ISSN:	1742-4933, 1742-4933
Online Access:	Get full text
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