Family income, parental education and brain structure in children and adolescents

Socioeconomic status is associated with cognitive development, but the extent to which this reflects neuroanatomical differences is unclear. In 1,099 children and adolescents, family income was nonlinearly associated with brain surface area, and this association was greatest among disadvantaged chil...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Nature neuroscience Jg. 18; H. 5; S. 773 - 778
Hauptverfasser: Noble, Kimberly G, Houston, Suzanne M, Brito, Natalie H, Bartsch, Hauke, Kan, Eric, Kuperman, Joshua M, Akshoomoff, Natacha, Amaral, David G, Bloss, Cinnamon S, Libiger, Ondrej, Schork, Nicholas J, Murray, Sarah S, Casey, B J, Chang, Linda, Ernst, Thomas M, Frazier, Jean A, Gruen, Jeffrey R, Kennedy, David N, Van Zijl, Peter, Mostofsky, Stewart, Kaufmann, Walter E, Kenet, Tal, Dale, Anders M, Jernigan, Terry L, Sowell, Elizabeth R
Format: Journal Article
Sprache:Englisch
Veröffentlicht: New York Nature Publishing Group US 01.05.2015
Nature Publishing Group
Schlagworte:
59/57
631/378/1831
631/378/2649
692/698/1688/64
706/689
Adolescent
Age Factors
Animal Genetics and Genomics
Anthropometry
Behavioral Sciences
Biological Techniques
Biomedicine
Brain - anatomy & histology
Brain - growth & development
Brain research
Cerebral Cortex - anatomy & histology
Cerebral Cortex - growth & development
Child
Child development
Child, Preschool
Cognition in children
DNA - genetics
Education
Educational Status
Family income
Genotype
Health aspects
Hippocampus - anatomy & histology
Hippocampus - growth & development
Hospitals
Humans
Income
Medicine
Models, Neurological
Neurobiology
Neurology
Neurosciences
Organ Size
Parents - education
Pediatrics
Poverty
Psychological Tests
Psychology, Adolescent
Psychology, Child
Regression Analysis
Social classes
Socioeconomic Factors
Young Adult
New York
Los Angeles California
La Jolla California
United States > US
Massachusetts
Connecticut
California
Maryland
Baltimore Maryland
ISSN:1097-6256, 1546-1726, 1546-1726
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Socioeconomic status is associated with cognitive development, but the extent to which this reflects neuroanatomical differences is unclear. In 1,099 children and adolescents, family income was nonlinearly associated with brain surface area, and this association was greatest among disadvantaged children. Further, surface area mediated links between income and executive functioning. Socioeconomic disparities are associated with differences in cognitive development. The extent to which this translates to disparities in brain structure is unclear. We investigated relationships between socioeconomic factors and brain morphometry, independently of genetic ancestry, among a cohort of 1,099 typically developing individuals between 3 and 20 years of age. Income was logarithmically associated with brain surface area. Among children from lower income families, small differences in income were associated with relatively large differences in surface area, whereas, among children from higher income families, similar income increments were associated with smaller differences in surface area. These relationships were most prominent in regions supporting language, reading, executive functions and spatial skills; surface area mediated socioeconomic differences in certain neurocognitive abilities. These data imply that income relates most strongly to brain structure among the most disadvantaged children.
Bibliographie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
ObjectType-Article-2
ObjectType-Feature-1
content type line 23
Denotes equal contribution to the development of the manuscript
ISSN:1097-6256
1546-1726
1546-1726
DOI:10.1038/nn.3983