Serologic Responses to Recombinant Pneumocystis jirovecii Major Surface Glycoprotein among Ugandan Patients with Respiratory Symptoms

Little is known about the serologic responses to Pneumocystis jirovecii major surface glycoprotein (Msg) antigen in African cohorts, or the IgM responses to Msg in HIV-positive and HIV-negative persons with respiratory symptoms. We conducted a prospective study of 550 patients, both HIV-positive (n...

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Bibliographic Details
Published in:	PloS one Vol. 7; no. 12; p. e51545
Main Authors:	Blount, Robert J., Jarlsberg, Leah G., Daly, Kieran R., Worodria, William, Davis, J. Lucian, Cattamanchi, Adithya, Djawe, Kpandja, Andama, Alfred, Koch, Judith, Walzer, Peter D., Huang, Laurence
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 21.12.2012 Public Library of Science (PLoS)
Subjects:	Acquired immune deficiency syndrome Adolescent Adult AIDS AIDS-Related Opportunistic Infections - blood AIDS-Related Opportunistic Infections - immunology AIDS-Related Opportunistic Infections - microbiology Antibodies, Fungal - blood Antigens Biology Biomarkers - blood CD4 antigen Cigarette smoking Collaboration Cough Critical care Cross infection Environmental health Enzyme-Linked Immunosorbent Assay Epidemiology Female Fungal Proteins - blood Fungal Proteins - genetics Fungal Proteins - immunology Gene expression Glycoproteins HIV HIV - pathogenicity HIV Infections - complications HIV Infections - microbiology HIV Infections - virology Hospital Mortality Hospital patients Hospitals Human immunodeficiency virus Humans Immunoglobulin G Immunoglobulin G - blood Immunoglobulin G - immunology Immunoglobulin M Immunoglobulin M - blood Immunoglobulin M - immunology Immunology Immunosuppression Infections Infectious diseases Internal medicine Male Medical diagnosis Medical research Medicine Membrane Glycoproteins - blood Membrane Glycoproteins - genetics Membrane Glycoproteins - immunology Middle Aged Mortality Patients Pneumocystis carinii - immunology Pneumonia Pneumonia, Pneumocystis - blood Pneumonia, Pneumocystis - immunology Pneumonia, Pneumocystis - microbiology Prophylaxis Prospective Studies Recombinant Proteins - blood Recombinant Proteins - genetics Recombinant Proteins - immunology Respiratory symptoms Risk Factors Smoking Studies Tuberculosis Uganda Young Adult Uganda San Francisco California Ohio California United States > US Kampala Uganda
ISSN:	1932-6203, 1932-6203
Online Access:	Get full text
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