Prevalence of benign osseous lesions of the spine and association with spinal pain in the general population in whole body MRI

Benign osseous lesions of the spine are common but precise population prevalence estimates are lacking. Our study aimed to provide the first population-based prevalence estimates and examine association with back and neck pain. We used data from the population-based Study of Health in Pomerania (SHI...

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Bibliographic Details
Published in:PloS one Vol. 14; no. 9; p. e0219846
Main Authors: Kasch, Richard, Scheele, Josephin, Hancock, Mark, Hofer, André, Maher, Christopher, Bülow, Robin, Lange, Jörn, Lahm, Andreas, Napp, Matthias, Wassilew, Georgi, Schmidt, Carsten Oliver
Format: Journal Article
Language:English
Published: United States Public Library of Science 09.09.2019
Public Library of Science (PLoS)
Subjects:
Adult
Age Factors
Aged
Analysis
Aneurysm
Back pain
Back Pain - diagnostic imaging
Back Pain - epidemiology
Back Pain - pathology
Back Pain - physiopathology
Benign
Biology and Life Sciences
Bone Cysts, Aneurysmal - diagnostic imaging
Bone Cysts, Aneurysmal - epidemiology
Bone Cysts, Aneurysmal - pathology
Bone surgery
Care and treatment
Cervical Vertebrae - diagnostic imaging
Cervical Vertebrae - innervation
Cervical Vertebrae - pathology
Connective tissue tumors
Cysts
Diagnosis
Diagnostic imaging
Female
Germany - epidemiology
Hemangioma
Hemangioma - diagnostic imaging
Hemangioma - epidemiology
Hemangioma - pathology
Humans
Lesions
Lipoma
Lipoma - diagnostic imaging
Lipoma - epidemiology
Lipoma - pathology
Lumbar Vertebrae - diagnostic imaging
Lumbar Vertebrae - innervation
Lumbar Vertebrae - pathology
Magnetic Resonance Imaging
Male
Medicine
Medicine and Health Sciences
Middle Aged
Neck
Neck pain
Neck Pain - diagnostic imaging
Neck Pain - epidemiology
Neck Pain - pathology
Neck Pain - physiopathology
NMR
Nuclear magnetic resonance
Observer Variation
Orthopedics
Outpatient care facilities
Pain
Population
Population studies
Prevalence
Prevalence studies (Epidemiology)
Public health
Rehabilitation
Reproducibility of Results
Research and Analysis Methods
Sclerosis
Sex Factors
Ships
Social Sciences
Society
Spine
Studies
Systematic review
Trauma
Germany
Sydney New South Wales Australia
Australia
ISSN:1932-6203, 1932-6203
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Summary:Benign osseous lesions of the spine are common but precise population prevalence estimates are lacking. Our study aimed to provide the first population-based prevalence estimates and examine association with back and neck pain. We used data from the population-based Study of Health in Pomerania (SHIP). Whole-body MRI examinations (1.5 Tesla: T1, T2, and TIRM weightings) were available from 3,259 participants. Readings of the spinal MRI images were conducted according to a standardized protocol by a single reader (JS). The intra-rater reliability was greater than Kappa values of 0.98. Pain measures included the seven-day prevalence of spine pain and neck pain, and average spine pain intensity due to spine pain during the past three months. We found 1,200 (36.8%) participants with at least one osseous lesion (2,080 lesions in total). Osseous lesions were less common in men than in women (35.5% vs 38.9%; P = .06). The prevalence of osseous lesions was highest at L2 in both sexes. The prevalence of osseous lesions increased with age. Up to eight osseous lesions were observed in a single subject. Hemangioma (28%), and lipoma (13%) occurred most often. Sclerosis (1.7%), aneurysmal bone cysts (0.7%), and blastoma (0.3%) were rare. Different osseous lesions occurred more often in combination with each other. The association with back or neck pain was mostly negligible. Osseous lesions are common in the general population but of no clinical relevance for spinal pain. The prevalence of osseous lesions varied strongly across different regions of the spine and was also associated with age and gender. Our population-based data offer new insights and assist in judging the relevance of osseous lesions observed on MRIs of patients.
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Competing Interests: The authors have declared that no competing interests exist.
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0219846