Histology Verification Demonstrates That Biospectroscopy Analysis of Cervical Cytology Identifies Underlying Disease More Accurately than Conventional Screening: Removing the Confounder of Discordance

Subjective visual assessment of cervical cytology is flawed, and this can manifest itself by inter- and intra-observer variability resulting ultimately in the degree of discordance in the grading categorisation of samples in screening vs. representative histology. Biospectroscopy methods have been s...

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Bibliographic Details
Published in:	PloS one Vol. 9; no. 1; p. e82416
Main Authors:	Gajjar, Ketan, Ahmadzai, Abdullah A., Valasoulis, George, Trevisan, Júlio, Founta, Christina, Nasioutziki, Maria, Loufopoulos, Aristotelis, Kyrgiou, Maria, Stasinou, Sofia Melina, Karakitsos, Petros, Paraskevaidis, Evangelos, Da Gama-Rose, Bianca, Martin-Hirsch, Pierre L., Martin, Francis L.
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 03.01.2014 Public Library of Science (PLoS)
Subjects:	Accuracy Biopsy Categories Cellular biology Cervical cancer Chemical bonds Cytodiagnosis - methods Cytodiagnosis - standards Cytology Deoxyribonucleic acid Diagnostic software Diagnostic systems Discordance Discriminant analysis DNA Early Detection of Cancer Evaluation Female Fourier transforms Gynecology Health screening Histology Human papillomavirus Humans Infrared spectroscopy Laboratories Medical screening Multivariate analysis Obstetrics Principal components analysis Screening Sensitivity and Specificity Sensors Spectral bands Spectral sensitivity Spectroscopy Spectroscopy, Fourier Transform Infrared Spectrum analysis Systematic review Uterine Cervical Neoplasms - diagnosis Uterine Cervical Neoplasms - pathology Vaginal Smears United Kingdom > UK
ISSN:	1932-6203, 1932-6203
Online Access:	Get full text
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