Clinical relevance of kallikrein-related peptidase 9, 10, 11, and 15 mRNA expression in advanced high-grade serous ovarian cancer

KLK9, 10, 11, and 15 may represent potential cancer biomarkers for evaluating ovarian cancer prognosis. In the present study, we selected a homogeneous cohort including 139 patients of advanced high-grade serous ovarian cancer (FIGO stage III/IV) and assessed the mRNA levels of KLK9, 10, 11, and 15...

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Bibliographic Details
Published in:	PloS one Vol. 12; no. 11; p. e0186847
Main Authors:	Geng, Xiaocong, Liu, Yueyang, Diersch, Sandra, Kotzsch, Matthias, Grill, Sabine, Weichert, Wilko, Kiechle, Marion, Magdolen, Viktor, Dorn, Julia
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 02.11.2017 Public Library of Science (PLoS)
Subjects:	Ascitic fluid Bioindicators Biology and Life Sciences Biomarkers Breast cancer Cancer Colon Disease Progression Female Gene expression Genetic aspects Gynecology Humans Kallikrein Kallikreins - genetics Medical prognosis Medicine and Health Sciences Messenger RNA Obstetrics Ovarian cancer Ovarian carcinoma Ovarian Neoplasms - enzymology Ovarian Neoplasms - pathology Patients Peptidase Peptidases Polymerase chain reaction Prognosis Quality Real-Time Polymerase Chain Reaction Regression analysis RNA, Messenger - genetics Studies Survival Survival Rate Thyroid gland Tumors
ISSN:	1932-6203, 1932-6203
Online Access:	Get full text
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