Polymorphisms of Immunity Genes and Susceptibility to Otitis Media in Children

Acute otitis media (OM) is a common disease which often develops through complex interactions between the host, the pathogen and environmental factors. We studied single nucleotide polymorphisms (SNPs) of genes involved in innate and adaptive immunity, and other host and environmental factors for th...

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Bibliographic Details
Published in:	PloS one Vol. 9; no. 4; p. e93930
Main Authors:	Nokso-Koivisto, Johanna, Chonmaitree, Tasnee, Jennings, Kristofer, Matalon, Reuben, Block, Stan, Patel, Janak A.
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 01.04.2014 Public Library of Science (PLoS)
Subjects:	Adaptive immunity Adaptive Immunity - genetics Age Alleles Analysis Biology and Life Sciences Breastfeeding & lactation Care and treatment Chemokines Child Child, Preschool Children CX3C Chemokine Receptor 1 CX3CR1 protein Cytokines Data processing Development and progression Disease susceptibility Ear diseases Environmental factors Female Follow-Up Studies Gene Frequency Generalized linear models Genes Genetic aspects Genetic polymorphisms Genetic Predisposition to Disease Genetics Genotype Health risks Humans Immunity Immunity, Innate - genetics Infant Infections Infectious diseases Interleukin 10 Interleukin 5 Interleukin 8 Interleukins - genetics Interleukins - physiology Male Medicine and Health Sciences Otitis media Otitis Media - epidemiology Otitis Media - genetics Otitis Media - immunology Otolaryngology Pediatrics Polymorphism, Single Nucleotide Prospective Studies Receptors, Chemokine - genetics Receptors, Chemokine - physiology Respiratory syncytial virus Respiratory Tract Infections - epidemiology Respiratory Tract Infections - genetics Respiratory Tract Infections - immunology Retrospective Studies Risk Risk factors Single-nucleotide polymorphism Studies Vaccines Viral infections Virus Diseases - genetics Virus Diseases - immunology Texas Kentucky United States > US
ISSN:	1932-6203, 1932-6203
Online Access:	Get full text
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