Systemic Lupus Erythematosus and Vitamin D Deficiency Are Associated with Shorter Telomere Length among African Americans: A Case-Control Study

Systemic lupus erythematosus (SLE) is a chronic systemic autoimmune disease that disproportionately affects African American females. The causes of SLE are unknown but postulated to be a combination of genetic predisposition and environmental triggers. Vitamin D deficiency is one of the possible env...

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Vydáno v:	PloS one Ročník 8; číslo 5; s. e63725
Hlavní autoři:	Hoffecker, Brett M., Raffield, Laura M., Kamen, Diane L., Nowling, Tamara K.
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States Public Library of Science 20.05.2013 Public Library of Science (PLoS)
Témata:	25-Hydroxyvitamin D Adult African American women African Americans African Americans - genetics Aging Antibodies Autoimmune diseases Biology Biomarkers Case-Control Studies Chromosomes Chronic conditions Correlation Deoxyribonucleic acid Disease control DNA Enzyme-linked immunosorbent assay Female Females Humans Leukocytes (mononuclear) Lupus Lupus Erythematosus, Systemic - blood Lupus Erythematosus, Systemic - genetics Medical research Medicine Middle Aged Minority & ethnic groups Multiplexing Patients Peripheral blood mononuclear cells Population studies Radioimmunoassay Systemic lupus erythematosus Telomere - genetics Telomere Homeostasis Telomeres Vitamin D Vitamin D - blood Vitamin D deficiency Vitamin D Deficiency - blood Vitamin D Deficiency - genetics Vitamin deficiency United States > US South Carolina
ISSN:	1932-6203, 1932-6203
On-line přístup:	Získat plný text
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