Temperature sensitive liposomes combined with thermal ablation: Effects of duration and timing of heating in mathematical models and in vivo

Temperature sensitive liposomes (TSL) are nanoparticles that rapidly release the contained drug at hyperthermic temperatures, typically above ~40°C. TSL have been combined with various heating modalities, but there is no consensus on required hyperthermia duration or ideal timing of heating relative...

Full description

Saved in:

Bibliographic Details
Published in:	PloS one Vol. 12; no. 6; p. e0179131
Main Authors:	Rossmann, Christian, McCrackin, M. A., Armeson, Kent E., Haemmerich, Dieter
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 12.06.2017 Public Library of Science (PLoS)
Subjects:	Ablation Algorithms Animal models Animals Area Under Curve Biology and Life Sciences Coagulation Computer and Information Sciences Computer applications Computer models Computer Simulation Correlation analysis Deposition Doxorubicin Drug delivery Drug Delivery Systems Drug dosages Electrodes Encapsulation Female Fever Fluorescence Heat transfer Heating Hyperthermia Hyperthermia, Induced Imaging In vivo methods and tests Infusion Liposomes Liver Liver cancer Mathematical analysis Mathematical models Medicine and Health Sciences Models, Theoretical Nanoparticles NMR Nuclear magnetic resonance Optimization Pediatrics Plasma Radiofrequency ablation Research and Analysis Methods Simulation Spatial analysis Spatial distribution Studies Swine Temperature Temperature effects Tissue Distribution Tumors Ultrasonic imaging United States > US South Carolina
ISSN:	1932-6203, 1932-6203
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!