Two Human Cases of Fatal Meningoencephalitis Associated with Potosi and Lone Star Virus Infections, United States, 2020–2023

We used clinical metagenomic next-generation sequencing of cerebrospinal fluid to investigate bunyavirus infections in 2 immunocompromised patients in the United States who had fatal meningoencephalitis. Potosi virus has been isolated from mosquito vectors and Lone Star virus from tick vectors. Thes...

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Bibliographic Details
Published in:	Emerging infectious diseases Vol. 31; no. 2; pp. 215 - 221
Main Authors:	Chiu, Charles Y., Godasi, Raja Rama, Hughes, Holly R., Servellita, Venice, Foresythe, Kafaya, Tubati, Asritha, Zorn, Kelsey, Sidhu, Sukhman, Wilson, Michael R., Bethina, Sai Varun, Abenroth, Daniel, Cheng, Yee, Grams, Raymond, Reese, Camilla, Isada, Carlos, Thottempudi, Neeharika
Format:	Journal Article
Language:	English
Published:	United States U.S. National Center for Infectious Diseases 01.02.2025 Centers for Disease Control and Prevention
Subjects:	Animals Antibiotics Bunyaviridae Infections - diagnosis Bunyaviridae Infections - epidemiology Bunyaviridae Infections - virology bunyavirus Case studies Causes of Cerebrospinal fluid Diagnostic tests Disease control Disease transmission Electroencephalography Encephalitis Virus, California - genetics Fatal Outcome Female Genetic vectors Genomes Glucose High-Throughput Nucleotide Sequencing Humans Infection Infections Leukocytes Lone Star virus LSV Magnetic resonance imaging Male Medical laboratories Medical research Medicine, Experimental Meningoencephalitis Meningoencephalitis - diagnosis Meningoencephalitis - epidemiology Meningoencephalitis - etiology Meningoencephalitis - virology Middle Aged Phylogeny Potosi virus POTV Proteins RNA virus infections Tuberculosis Two Human Cases of Fatal Meningoencephalitis Associated with Potosi and Lone Star Virus Infections, United States, 2020–2023 United States - epidemiology Vector-borne diseases Viruses United States California United States > US San Francisco California Ohio mosquitoes viruses POTV United States ticks Lone Star virus metagenomic next-generation sequencing Potosi virus LSV arthropod-borne viruses meningoencephalitis vector-borne infections Amyblomma americanum tick arboviruses bunyavirus Aedes albopictus mosquito meningitis/encephalitis mNGS
ISSN:	1080-6040, 1080-6059, 1080-6059
Online Access:	Get full text
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