Role of the innate immune system in the pathogenesis of multiple sclerosis

Multiple sclerosis (MS) is a chronic inflammatory autoimmune disease with heterogeneous clinical presentations and course. MS is considered to be a T cell mediated disease but in recent years contribution of innate immune cells in mediating MS pathogenesis is being appreciated. In this review, we ha...

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Bibliographic Details
Published in:	Journal of neuroimmunology Vol. 221; no. 1; pp. 7 - 14
Main Authors:	Gandhi, Roopali, Laroni, Alice, Weiner, Howard L.
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier B.V 15.04.2010
Subjects:	Allergy and Immunology Animals Cytokines - metabolism Dendritic cells Dendritic Cells - physiology Gamma Delta T cells Humans Immunity, Innate - physiology Innate immune system Killer Cells, Natural - physiology Mast cells Mast Cells - physiology Microglia - physiology Microglial cells Models, Immunological Multiple sclerosis Multiple Sclerosis - etiology Multiple Sclerosis - immunology Multiple Sclerosis - pathology Neurology NK cells NK T cells T-Lymphocytes - classification T-Lymphocytes - physiology Multiple sclerosis NK cells Gamma Delta T cells Dendritic cells Microglial cells NK T cells Mast cells Innate immune system
ISSN:	0165-5728, 1872-8421, 1872-8421
Online Access:	Get full text
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