Evaluation of choroidal layer thickness in central serous chorioretinopathy

Purpose: To evaluate medium and large choroidal vessel layer thickness (MCVT and LCVT, respectively) in eyes with acute and chronic central serous chorioretinopathy (CSC) in comparison with age-matched controls. Methods: The study included 96 eyes of 96 patients with CSC, including 53 eyes with acut...

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Vydáno v:Journal of ophthalmic & vision research Ročník 14; číslo 2; s. 164 - 170
Hlavní autoři: Hanumunthadu, Daren, van Dijk, Elon, Dumpala, Sunila, Rajesh, Bindu, Jabeen, Ayesha, Jabeen, Asiya, Ansari, Momin, Mehta, Pooja, Shah, Shilpi, Sarvaiya, Chintan, Meyerle, Catherine, Wu, Lihteh, Banker, Alay, Boon, Camiel, Chhablani, Jay
Médium: Journal Article
Jazyk:angličtina
Vydáno: United Arab Emirates Wolters Kluwer India Pvt. Ltd 01.04.2019
Medknow Publications and Media Pvt. Ltd
Medknow Publications & Media Pvt. Ltd
Wolters Kluwer - Medknow
Knowledge E
Témata:
Age
Central Serous Chorioretinopathy; Choroid; Optical Coherence Tomography
Chronic illnesses
Clinical trials
Family medical history
Medical imaging
Medical research
Medicine, Experimental
Original
Patients
Photodynamic therapy
Software
United States > US
Netherlands
India
Choroid
Optical Coherence Tomography
Central Serous Chorioretinopathy
ISSN:2008-322X, 2008-2010, 2008-322X
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Shrnutí:Purpose: To evaluate medium and large choroidal vessel layer thickness (MCVT and LCVT, respectively) in eyes with acute and chronic central serous chorioretinopathy (CSC) in comparison with age-matched controls. Methods: The study included 96 eyes of 96 patients with CSC, including 53 eyes with acute CSC, 43 eyes with chronic CSC, and 30 eyes of 30 age-matched normal subjects. Manual measurements of subfoveal choroidal thickness (SFCT), MCVT, and LCVT at subfoveal and 750 μm nasal and temporal to the fovea locations were made on enhanced depth imaging optical coherence tomography (EDI-OCT) of the macula in all subjects using ImageJ software (National Institutes of Health, Bethesda, MD, USA). Results: SFCT in acute CSC was significantly larger than that in healthy eyes (P = 0.0001). SFCT in acute CSC did not differ significantly from that in chronic CSC eyes. Subfoveal LCVT and MCVT in acute CSC eyes were greater than those in healthy eyes (P = 0.02 and P = 0.03, respectively). Mean SFCT and MCVT in chronic CSC eyes were significantly larger than those in control eyes (P = 0.01 and P = 0.04, respectively). No significant difference in LCVT was observed between chronic and control eyes. Conclusion: Choroidal vasculature is altered in both acute and chronic CSC. SFCT, MCVT, and LCVT are higher in eyes with acute CSC. The thickening of medium choroidal vessels is still detectable in chronic CSC compared to control eyes.
Bibliografie:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:2008-322X
2008-2010
2008-322X
DOI:10.4103/jovr.jovr_152_17