Mitochondrial uncoupling protein gene cluster variation (UCP2–UCP3) and the risk of incident type 2 diabetes mellitus: The Women's Genome Health Study

Uncoupling protein 2, mitochondrial, (UCP2) gene variation has recently been implicated in type 2 diabetes mellitus (T2DM). To date, no prospective epidemiological data are available. The association between 14 UCP (UCP2–UCP3) gene cluster tagging-SNPs and incident T2DM was investigated in 22,715 Ca...

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Vydáno v:	Atherosclerosis Ročník 214; číslo 1; s. 107 - 109
Hlavní autoři:	Zee, Robert Y.L., Ridker, Paul M, Chasman, Daniel I.
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	Amsterdam Elsevier Ireland Ltd 01.01.2011 Elsevier
Témata:	Associated diseases and complications atherosclerosis Atherosclerosis (general aspects, experimental research) Biological and medical sciences Blood and lymphatic vessels Cardiology. Vascular system Cardiovascular Cohort Studies Diabetes Mellitus, Type 2 Diabetes Mellitus, Type 2 - diagnosis Diabetes Mellitus, Type 2 - genetics Diabetes. Impaired glucose tolerance diagnosis Endocrine pancreas. Apud cells (diseases) Endocrinopathies Female Follow-Up Studies Gene variation genes Genetic Variation genetics Haplotypes Humans Ion Channels Ion Channels - genetics Medical sciences Middle Aged Mitochondrial Proteins Mitochondrial Proteins - genetics Multivariate Analysis noninsulin-dependent diabetes mellitus Proportional Hazards Models Prospective Studies regression analysis Risk Risk Assessment Risk factors Type 2 diabetes UCPs Uncoupling Protein 2 Uncoupling Protein 3 women Type 2 diabetes UCPs Risk factors Gene variation Endocrinopathy Human Metabolic diseases Cluster Cardiovascular disease Vascular disease Atherosclerosis Risk factor Genome
ISSN:	0021-9150, 1879-1484, 1879-1484
On-line přístup:	Získat plný text
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